BAX Ab
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BAX Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
BAX Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
BAX Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
BAX Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
BAX Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
BAX Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
BAX Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
BAX Ab
Western blot analysis of Bax in (1) HeLa cell lysate;(2) RAW264.7 Whole Cell Lysate.

产品简介

Product Introduction

Catalog No.

CY5059

Source

Recombinant Rabbit mAb

UniProt ID

Q07812

Reactivity

Human;Mouse;Rat;Hamster

Application

WB;IHC;IP;FC

Calculated Mol Weight

21 kDa

Observed Mol Weight

21 kDa

Recommended Dilution

WB 1:1000-1:2000

IHC 1:100-1:200

IP 1:20-1:50

FC 1:20-1:100

Alternative Names

Apoptosis regulator BAX; BAX; Bcl-2-like protein 4; BCL2-associated X protein; Bcl2-L-4; BCL2L4

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human BAX

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Bax is a key component for cellular induced apoptosis through mitochondrial stress. Upon apoptotic stimulation, Bax forms oligomers and translocates from the cytosol to the mitochondrial membrane. Through interactions with pore proteins on the mitochondrial membrane, Bax increases the membrane's permeability, which leads to the release of cytochrome c from mitochondria, activation of caspase-9 and initiation of the caspase activation pathway for apoptosis.

引用文献

Citation

Chloride intracellular channel 1 regulates the antineoplastic effects of metformin in gallbladder cancer cells

期刊名称：

CANCER SCIENCE

PMID：

28378944

影响因子：

3.974

应用范围：

WB

检测物种：

Human

发表时间：

2017-04-05
The PR-1 domain accounts for the anti-angiogenic activity of a cysteine-rich secretory protein member from the buccal glands of Lampetra japonica

期刊名称：

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

PMID：

29042283

影响因子：

3.671

应用范围：

WB

检测物种：

Human

发表时间：

2017-10-16
Taurine protects INS-1 cells from apoptosis induced by Di(2-ethylhexyl) phthalate via reducing oxidative stress and autophagy

期刊名称：

TOXICOLOGY MECHANISMS AND METHODS

PMID：

30890009

影响因子：

2.276

应用范围：

WB

检测物种：

Rat

发表时间：

2019-06-04
Salidroside induces apoptosis and protective autophagy in human gastric cancer AGS cells through the PI3K/Akt/mTOR pathway

期刊名称：

BIOMEDICINE & PHARMACOTHERAPY

PMID：

31918283

影响因子：

3.743

应用范围：

WB

检测物种：

Human

发表时间：

2019-12-30
Phenols fragment of Veronica ciliata Fisch. ameliorate free radical-induced nonalcoholic fatty liver disease by mediating PI3K/Akt signaling pathway

期刊名称：

JOURNAL OF ETHNOPHARMACOLOGY

PMID：

31978521

影响因子：

3.69

应用范围：

WB

检测物种：

Rat

发表时间：

2020-01-21
Progesterone attenuates Aβ25–35-induced neuronal toxicity by activating the Ras signalling pathway through progesterone receptor membrane component 1

期刊名称：

LIFE SCIENCES

PMID：

32001269

影响因子：

3.647

应用范围：

WB

检测物种：

Rat

发表时间：

2020-01-27

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CY5059

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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