BAX Ab
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BAX Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
BAX Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
BAX Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
BAX Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
BAX Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
BAX Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
BAX Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
BAX Ab
Western blot analysis of Bax in (1) HeLa cell lysate;(2) RAW264.7 Whole Cell Lysate.
BAX Ab
Taurine protects INS-1 cells from apoptosis induced by Di(2-ethylhexyl) phthalate via reducing oxidative stress and autophagy. -Toxicology Mechanisms and Methods
BAX Ab
Mechanistic insights into geniposide regulation of bile salt export pump (BSEP) expression. -RSC Advances
BAX Ab
Chloride intracellular channel 1 regulates the antineoplastic effects of metformin in gallbladder cancer cells. -cancer science
BAX Ab
Immunohistochemical analysis of paraffin-embedded Human lung adenocarcinoma, using the Antibody at 1:200 dilution.

产品简介

Product Introduction

Catalog No.

CY5059

Source

Recombinant Rabbit mAb

UniProt ID

Q07812

Reactivity

Human;Mouse;Rat;Hamster

Application

WB;IHC;IP;FC

Calculated Mol Weight

21 kDa

Observed Mol Weight

21 kDa

Recommended Dilution

WB 1:1000-1:2000

IHC 1:100-1:200

IP 1:20-1:50

FC 1:20-1:100

Alternative Names

Apoptosis regulator BAX; BAX; Bcl-2-like protein 4; BCL2-associated X protein; Bcl2-L-4; BCL2L4

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human BAX

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Bax is a key component for cellular induced apoptosis through mitochondrial stress. Upon apoptotic stimulation, Bax forms oligomers and translocates from the cytosol to the mitochondrial membrane. Through interactions with pore proteins on the mitochondrial membrane, Bax increases the membrane's permeability, which leads to the release of cytochrome c from mitochondria, activation of caspase-9 and initiation of the caspase activation pathway for apoptosis.

引用文献

Citation

CRISPR-Cas9-Mediated NPC1 Gene Deletion Enhances HEK 293 T Cell Adhesion by Regulating E-Cadherin

期刊名称：

MOLECULAR BIOTECHNOLOGY

PMID：

35587334

影响因子：

2.86

应用范围：

WB

检测物种：

Human

发表时间：

2022-05-19
Resveratrol improves estrus disorder induced by bisphenol A through attenuating oxidative stress, autophagy, and apoptosis

期刊名称：

JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

PMID：

35670589

影响因子：

3.568

应用范围：

WB

检测物种：

Mouse

发表时间：

2022-06-07
SKLB-14b, a novel oral microtubule-destabilizing agent based on hydroxamic acid with potent anti-tumor and anti-multidrug resistance activities

期刊名称：

BIOORGANIC CHEMISTRY

PMID：

35964504

影响因子：

5.307

应用范围：

WB

检测物种：

Human

发表时间：

2022-08-01
Chaetoglobosin E inhibits tumor growth and promotes the anti-tumor efficacy of cytotoxic drugs in esophageal squamous cell carcinoma by targeting PLK1

期刊名称：

Annals of Translational Medicine

PMID：

36544631

影响因子：

3.616

应用范围：

WB

检测物种：

Human

发表时间：

2022-11-01
Dulaglutide Improves Gliosis and Suppresses Apoptosis/Autophagy Through the PI3K/Akt/mTOR Signaling Pathway in Vascular Dementia Rats

期刊名称：

NEUROCHEMICAL RESEARCH

PMID：

36571662

影响因子：

4.414

应用范围：

WB

检测物种：

Rat

发表时间：

2022-12-26
Alfalfa Xeno-miR168b Target CPT1A to Regulate Milk Fat Synthesis in Bovine Mammary Epithelial Cells

期刊名称：

Metabolites

PMID：

36677001

影响因子：

4.1

应用范围：

WB

检测物种：

Bovine

发表时间：

2023-01-03

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CY5059

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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