BAX Ab
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BAX Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
BAX Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
BAX Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
BAX Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
BAX Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
BAX Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
BAX Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
BAX Ab
Western blot analysis of Bax in (1) HeLa cell lysate;(2) RAW264.7 Whole Cell Lysate.

产品简介

Product Introduction

Catalog No.

CY5059

Source

Recombinant Rabbit mAb

UniProt ID

Q07812

Reactivity

Human;Mouse;Rat;Hamster

Application

WB;IHC;IP;FC

Calculated Mol Weight

21 kDa

Observed Mol Weight

21 kDa

Recommended Dilution

WB 1:1000-1:2000

IHC 1:100-1:200

IP 1:20-1:50

FC 1:20-1:100

Alternative Names

Apoptosis regulator BAX; BAX; Bcl-2-like protein 4; BCL2-associated X protein; Bcl2-L-4; BCL2L4

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human BAX

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Bax is a key component for cellular induced apoptosis through mitochondrial stress. Upon apoptotic stimulation, Bax forms oligomers and translocates from the cytosol to the mitochondrial membrane. Through interactions with pore proteins on the mitochondrial membrane, Bax increases the membrane's permeability, which leads to the release of cytochrome c from mitochondria, activation of caspase-9 and initiation of the caspase activation pathway for apoptosis.

引用文献

Citation

CircRNA_103765 acts as a proinflammatory factor via sponging miR-30 family in Crohn’s disease

期刊名称：

Scientific Reports

PMID：

33436852

影响因子：

4.38

应用范围：

WB

检测物种：

Human

发表时间：

2021-01-12
The antiandrogenic effect of neferine, liensinine, and isoliensinine by inhibiting 5-α-reductase and androgen receptor expression via PI3K/AKT signaling pathway in prostate cancer

期刊名称：

PHARMAZIE

PMID：

33964997

影响因子：

1.267

应用范围：

WB

检测物种：

Human

发表时间：

2021-05-01
PD-1-siRNA Delivered by Attenuated Salmonella Enhances the Antitumor Effect of Chloroquine in Colon Cancer

期刊名称：

Frontiers in Immunology

PMID：

34295341

影响因子：

7.561

应用范围：

WB

检测物种：

Mouse,Human

发表时间：

2021-07-06
Based on Activation of p62-Keap1-Nrf2 Pathway, Hesperidin Protects Arsenic-Trioxide-Induced Cardiotoxicity in Mice

期刊名称：

Frontiers in Pharmacology

PMID：

34721041

影响因子：

5.811

应用范围：

WB

检测物种：

Mouse

发表时间：

2021-10-13
Neuroprotective effects of liraglutide against inflammation through the AMPK/NF-κB pathway in a mouse model of Parkinson’s disease

期刊名称：

METABOLIC BRAIN DISEASE

PMID：

34817756

影响因子：

3.584

应用范围：

WB

检测物种：

Mouse

发表时间：

2021-11-24
Clinical significance and biological functions of chemokine CXCL3 in head and neck squamous cell carcinoma

期刊名称：

BIOSCIENCE REPORTS

PMID：

34870709

影响因子：

3.84

应用范围：

WB

检测物种：

Human

发表时间：

2021-12-22

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CY5059

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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