BAX Ab
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BAX Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
BAX Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
BAX Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
BAX Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
BAX Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
BAX Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
BAX Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
BAX Ab
Western blot analysis of Bax in (1) HeLa cell lysate;(2) RAW264.7 Whole Cell Lysate.
BAX Ab
Taurine protects INS-1 cells from apoptosis induced by Di(2-ethylhexyl) phthalate via reducing oxidative stress and autophagy. -Toxicology Mechanisms and Methods
BAX Ab
Mechanistic insights into geniposide regulation of bile salt export pump (BSEP) expression. -RSC Advances
BAX Ab
Chloride intracellular channel 1 regulates the antineoplastic effects of metformin in gallbladder cancer cells. -cancer science
BAX Ab
Immunohistochemical analysis of paraffin-embedded Human lung adenocarcinoma, using the Antibody at 1:200 dilution.

产品简介

Product Introduction

Catalog No.

CY5059

Source

Recombinant Rabbit mAb

UniProt ID

Q07812

Reactivity

Human;Mouse;Rat;Hamster

Application

WB;IHC;IP;FC

Calculated Mol Weight

21 kDa

Observed Mol Weight

21 kDa

Recommended Dilution

WB 1:1000-1:2000

IHC 1:100-1:200

IP 1:20-1:50

FC 1:20-1:100

Alternative Names

Apoptosis regulator BAX; BAX; Bcl-2-like protein 4; BCL2-associated X protein; Bcl2-L-4; BCL2L4

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human BAX

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Bax is a key component for cellular induced apoptosis through mitochondrial stress. Upon apoptotic stimulation, Bax forms oligomers and translocates from the cytosol to the mitochondrial membrane. Through interactions with pore proteins on the mitochondrial membrane, Bax increases the membrane's permeability, which leads to the release of cytochrome c from mitochondria, activation of caspase-9 and initiation of the caspase activation pathway for apoptosis.

引用文献

Citation

OGR1 negatively regulates β-casein and triglyceride synthesis and cell proliferation via the PI3K/AKT/mTOR signaling pathway in goat mammary epithelial cells

期刊名称：

ANIMAL BIOTECHNOLOGY

PMID：

32167419

影响因子：

1.487

应用范围：

WB

检测物种：

Goat

发表时间：

2020-03-13
Inhibition of gastric cancer cell apoptosis by long noncoding RNA TRPM2-AS via mitogen-activated protein kinase and activators of transduction-3

期刊名称：

JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

PMID：

32424838

影响因子：

3.437

应用范围：

WB

检测物种：

Human

发表时间：

2020-05-18
Survival motor neuron protein protects H9c2 cardiomyocytes from hypoxia-induced cell injury by reducing apoptosis

期刊名称：

CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

PMID：

32603518

影响因子：

2.456

应用范围：

WB

检测物种：

Rat

发表时间：

2020-06-30
Ma xing shi gan decoction eliminates PM2.5-induced lung injury by reducing pulmonary cell apoptosis through Akt/mTOR/p70S6K pathway in rats

期刊名称：

BIOSCIENCE REPORTS

PMID：

32627816

影响因子：

2.942

应用范围：

WB

检测物种：

Human,Rat

发表时间：

2020-07-09
JLX001 improves myocardial ischemia-reperfusion injury by activating Jak2-Stat3 pathway

期刊名称：

LIFE SCIENCES

PMID：

32673665

影响因子：

3.647

应用范围：

WB

检测物种：

Rat

发表时间：

2020-07-14
CircRNA8220 Sponges MiR-8516 to Regulate Cell Viability and Milk Synthesis via Ras/MEK/ERK and PI3K/AKT/mTOR Pathways in Goat Mammary Epithelial Cells

期刊名称：

Animals

PMID：

32759741

影响因子：

2.323

应用范围：

WB

检测物种：

Goat

发表时间：

2020-08-04

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CY5059

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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