BAX Ab
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BAX Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
BAX Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
BAX Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
BAX Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
BAX Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
BAX Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
BAX Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
BAX Ab
Western blot analysis of Bax in (1) HeLa cell lysate;(2) RAW264.7 Whole Cell Lysate.

产品简介

Product Introduction

Catalog No.

CY5059

Source

Recombinant Rabbit mAb

UniProt ID

Q07812

Reactivity

Human;Mouse;Rat;Hamster

Application

WB;IHC;IP;FC

Calculated Mol Weight

21 kDa

Observed Mol Weight

21 kDa

Recommended Dilution

WB 1:1000-1:2000

IHC 1:100-1:200

IP 1:20-1:50

FC 1:20-1:100

Alternative Names

Apoptosis regulator BAX; BAX; Bcl-2-like protein 4; BCL2-associated X protein; Bcl2-L-4; BCL2L4

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human BAX

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Bax is a key component for cellular induced apoptosis through mitochondrial stress. Upon apoptotic stimulation, Bax forms oligomers and translocates from the cytosol to the mitochondrial membrane. Through interactions with pore proteins on the mitochondrial membrane, Bax increases the membrane's permeability, which leads to the release of cytochrome c from mitochondria, activation of caspase-9 and initiation of the caspase activation pathway for apoptosis.

引用文献

Citation

Npc1 gene mutation abnormally activates the classical Wnt signalling pathway in mouse kidneys and promotes renal fibrosis

期刊名称：

ANIMAL GENETICS

PMID：

38087834

影响因子：

2.4

应用范围：

WB

检测物种：

Mouse

发表时间：

2023-12-12
Nifuroxazide suppresses PD-L1 expression and enhances the efficacy of radiotherapy in hepatocellular carcinoma

期刊名称：

eLife

PMID：

38441416

影响因子：

6.4

应用范围：

WB,ICC/IF

检测物种：

Mouse,Human

发表时间：

2024-03-05
Inhibition of TNBC Cell Growth by Paroxetine: Induction of Apoptosis and Blockage of Autophagy Flux

期刊名称：

Cancers

PMID：

38473249

影响因子：

4.5

应用范围：

WB

检测物种：

Human,Mouse

发表时间：

2024-02-22
G6PD maintains the VSMC synthetic phenotype and accelerates vascular neointimal hyperplasia by inhibiting the VDAC1–Bax-mediated mitochondrial apoptosis pathway

期刊名称：

CELLULAR & MOLECULAR BIOLOGY LETTERS

PMID：

38589823

影响因子：

9.2

应用范围：

WB,IP

检测物种：

Rat

发表时间：

2024-04-08
Maslinic acid supplementation prevents di(2-ethylhexyl) phthalate-induced apoptosis via PRDX6 in peritubular myoid cells of Chinese forest musk deer

期刊名称：

Journal of Environmental Sciences

PMID：

38644023

影响因子：

6.9

应用范围：

IHC,ICC/IF,WB

检测物种：

Deer

发表时间：

2023-07-29
Exploring novel function of Gpx5 antioxidant activity: Assisting epididymal cells secrete functional extracellular vesicles

期刊名称：

JOURNAL OF CELLULAR PHYSIOLOGY

PMID：

38666419

影响因子：

4.5

应用范围：

WB,ICC/IF

检测物种：

Mouse

发表时间：

2024-04-26

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CY5059

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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