xCT Ab
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xCT Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
xCT Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
xCT Ab
Western blot analysis of xCT expression in (1) HepG2 cell lysate; (2) Mouse brain lysate.
xCT Ab
Immunofluorescent analysis using the Antibody at 1:50 dilution.
xCT Ab
Immunofluorescent analysis using the Antibody at 1:50 dilution.
xCT Ab
Immunofluorescent analysis using the Antibody at 1:150 dilution.
xCT Ab
Immunofluorescent analysis using the Antibody at 1:150 dilution.
xCT Ab

产品简介

Product Introduction

Catalog No.

CY7046

Source

Recombinant Rabbit mAb

UniProt ID

Q9UPY5

Reactivity

Human;Mouse;Rat

Application

WB;ICC/IF;IP

Calculated Mol Weight

55 kDa

Observed Mol Weight

55 kDa

Recommended Dilution

WB 1:1000-1:2000

ICC/IF 1:50-1:200

IP 1:20-1:50

Alternative Names

CCBR1; Cysteine/glutamate transporter; SLC7A11; solute carrier family 7; xCT;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human xCT

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Heterodimer with SLC3A2, that functions as an antiporter by mediating the exchange of extracellular anionic L-cystine and intracellular L-glutamate across the cellular plasma membrane.Provides L-cystine for the maintenance of the redox balance between extracellular L-cystine and L-cysteine and for the maintenance of the intracellular levels of glutathione that is essential for cells protection from oxidative stress.

引用文献

Citation

GPX4 degradation via chaperone-mediated autophagy contributes to antimony-triggered neuronal ferroptosis

期刊名称：

ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

PMID：

35305351

影响因子：

7.129

应用范围：

WB

检测物种：

Mouse,Rat

发表时间：

2022-03-16
Ferroptosis Is Involved in Sex-Specific Small Intestinal Toxicity in the Offspring of Adult Mice Exposed to Polystyrene Nanoplastics during Pregnancy

期刊名称：

ACS Nano

PMID：

36728677

影响因子：

17.1

应用范围：

WB

检测物种：

Mouse

发表时间：

2023-02-02
Yes-associated protein inhibition ameliorates liver fibrosis and acute and chronic liver failure by decreasing ferroptosis and necroptosis

期刊名称：

Heliyon

PMID：

37151632

影响因子：

4

应用范围：

IHC,WB

检测物种：

Mouse

发表时间：

2023-04-03
Moderate Intensity of Treadmill Exercise Rescues TBI-Induced Ferroptosis, Neurodegeneration, and Cognitive Impairments via Suppressing STING Pathway

期刊名称：

MOLECULAR NEUROBIOLOGY

PMID：

37193866

影响因子：

5.1

应用范围：

WB,ICC/IF

检测物种：

Mouse

发表时间：

2023-05-16
5-ALA-PDT induced ferroptosis in keloid fibroblasts via ROS, accompanied by downregulation of xCT, GPX4

期刊名称：

Photodiagnosis and Photodynamic Therapy

PMID：

37220842

影响因子：

3.3

应用范围：

WB

检测物种：

Human

发表时间：

2023-05-21
Heme oxygenase 1 alleviates nonalcoholic steatohepatitis by suppressing hepatic ferroptosis

期刊名称：

Lipids in Health and Disease

PMID：

37422643

影响因子：

4.5

应用范围：

WB,IHC

检测物种：

Mouse

发表时间：

2023-07-08

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CY7046

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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