xCT Ab
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xCT Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
xCT Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
xCT Ab
Western blot analysis of xCT expression in (1) HepG2 cell lysate; (2) Mouse brain lysate.
xCT Ab
Immunofluorescent analysis using the Antibody at 1:50 dilution.
xCT Ab
Immunofluorescent analysis using the Antibody at 1:50 dilution.
xCT Ab
Immunofluorescent analysis using the Antibody at 1:150 dilution.
xCT Ab
Immunofluorescent analysis using the Antibody at 1:150 dilution.
xCT Ab

产品简介

Product Introduction

Catalog No.

CY7046

Source

Recombinant Rabbit mAb

UniProt ID

Q9UPY5

Reactivity

Human;Mouse;Rat

Application

WB;ICC/IF;IP

Calculated Mol Weight

55 kDa

Observed Mol Weight

55 kDa

Recommended Dilution

WB 1:1000-1:2000

ICC/IF 1:50-1:200

IP 1:20-1:50

Alternative Names

CCBR1; Cysteine/glutamate transporter; SLC7A11; solute carrier family 7; xCT;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human xCT

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Heterodimer with SLC3A2, that functions as an antiporter by mediating the exchange of extracellular anionic L-cystine and intracellular L-glutamate across the cellular plasma membrane.Provides L-cystine for the maintenance of the redox balance between extracellular L-cystine and L-cysteine and for the maintenance of the intracellular levels of glutathione that is essential for cells protection from oxidative stress.

引用文献

Citation

Ozone pretreatment alleviates ischemiareperfusion injury-induced myocardial ferroptosis by activating the Nrf2/Slc7a11/Gpx4 axis

期刊名称：

BIOMEDICINE & PHARMACOTHERAPY

PMID：

37487441

影响因子：

7.5

应用范围：

ICC/IF,WB

检测物种：

Mouse

发表时间：

2023-07-22
Matrine disrupts Nrf2/GPX4 antioxidant system and promotes hepatocyte ferroptosis

期刊名称：

CHEMICO-BIOLOGICAL INTERACTIONS

PMID：

37716422

影响因子：

5.1

应用范围：

WB

检测物种：

Mouse,Human

发表时间：

2023-09-15
Sodium Selenite Prevents Matrine-Induced Nephrotoxicity by Suppressing Ferroptosis via the GSH-GPX4 Antioxidant System

期刊名称：

BIOLOGICAL TRACE ELEMENT RESEARCH

PMID：

38177716

影响因子：

3.4

应用范围：

WB

检测物种：

Human,Mouse

发表时间：

2024-01-04
Ozone-Mediated Cerebral Protection: Unraveling the Mechanism through Ferroptosis and the NRF2/SLC7A11/GPX4 Signaling Pathway

期刊名称：

JOURNAL OF CHEMICAL NEUROANATOMY

PMID：

38182039

影响因子：

2.7

应用范围：

WB

检测物种：

Rat

发表时间：

2024-01-03
Correlation of disulfidptosis and periodontitis: new insights and clinical significance

期刊名称：

ARCHIVES OF ORAL BIOLOGY

PMID：

38991331

影响因子：

2.2

应用范围：

ICC/IF

检测物种：

Rat,Human

发表时间：

2024-07-02
Dihydroisotanshinone I regulates ferroptosis via PI3K/AKT pathway to enhance cisplatin sensitivity in lung adenocarcinoma

期刊名称：

JOURNAL OF PHARMACY AND PHARMACOLOGY

PMID：

39045884

影响因子：

2.8

应用范围：

WB

检测物种：

Human

发表时间：

2024-07-23

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CY7046

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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