NLRP3 Ab
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NLRP3 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
NLRP3 Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
NLRP3 Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
NLRP3 Ab
Western blot analysis of NLRP3 expression in SH-SY5Y cell lysate.
NLRP3 Ab
NLRP3 Ab
PM2.5 exposure impairs sperm quality through testicular damage dependent on NALP3 inflammasome and miR-183/96/182 cluster targeting FOXO1 in mouse. -Ecotoxicology and Environmental Safety
NLRP3 Ab
Kynurenic acid/GPR35 axis restricts NLRP3 inflammasome activation and exacerbates colitis in mice with social stress. -BRAIN BEHAVIOR AND IMMUNITY
NLRP3 Ab
Immunohistochemical analysis of paraffin-embedded human lung carcinoma, using NALP3 Antibody.

产品简介

Product Introduction

Catalog No.

CY5651

Source

Recombinant Rabbit mAb

UniProt ID

Q96P20

Reactivity

Human;Mouse;Rat

Application

WB;IHC;ICC/IF;IHF

Calculated Mol Weight

118 kDa

Observed Mol Weight

118 kDa

Recommended Dilution

WB 1:1000-1:2000

IHC 1:100-1:200

ICC/IF 1:50-1:200

IHF 1:50-1:200

Alternative Names

FCU; MWS; FCAS; Cias1; Mmig1; NLRP3; Pypaf1; AII/AVP; AGTAVPRL; Cryopyrin;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human NLRP3

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Sensor component of the NLRP3 inflammasome, which mediates inflammasome activation in response to defects in membrane integrity, leading to secretion of inflammatory cytokines IL1B and IL18 and pyroptosis.

引用文献

Citation

PM2.5 exposure impairs sperm quality through testicular damage dependent on NALP3 inflammasome and miR-183/96/182 cluster targeting FOXO1 in mouse

期刊名称：

ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

PMID：

30476817

影响因子：

3.974

应用范围：

WB

检测物种：

Mouse

发表时间：

2018-11-24
Kynurenic acid/GPR35 axis restricts NLRP3 inflammasome activation and exacerbates colitis in mice with social stress

期刊名称：

BRAIN BEHAVIOR AND IMMUNITY

PMID：

30790702

影响因子：

6.17

应用范围：

WB

检测物种：

Mouse

发表时间：

2019-02-18
Inhibition of vascular neointima hyperplasia by FGF21 associated with FGFR1/Syk/NLRP3 inflammasome pathway in diabetic mice

期刊名称：

ATHEROSCLEROSIS

PMID：

31513948

影响因子：

4.255

应用范围：

WB,ICC/IF,IHC

检测物种：

Mouse

发表时间：

2019-08-29
Protective effects of acarbose against vascular endothelial dysfunction through inhibiting Nox4/NLRP3 inflammasome pathway in diabetic rats

期刊名称：

FREE RADICAL BIOLOGY AND MEDICINE

PMID：

31541678

影响因子：

5.657

应用范围：

WB,ICC/IF

检测物种：

Rat

发表时间：

2019-09-18
Carbon black nanoparticles induce pulmonary fibrosis through NLRP3 inflammasome pathway modulated by miR-96 targeted FOXO3a

期刊名称：

CHEMOSPHERE

PMID：

31683435

影响因子：

5.108

应用范围：

WB

检测物种：

Rat,Human

发表时间：

2019-10-11
Regulation of NLRP3 inflammasome by CD38 through cADPR-mediated Ca2+ release in vascular smooth muscle cells in diabetic mice

期刊名称：

LIFE SCIENCES

PMID：

32407845

影响因子：

3.647

应用范围：

WB,IHC,ICC/IF

检测物种：

Mouse

发表时间：

2020-05-11

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CY5651

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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>> All rabbit monoclonal antibody products targeting this target