NLRP3 Ab
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NLRP3 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
NLRP3 Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
NLRP3 Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
NLRP3 Ab
Western blot analysis of NLRP3 expression in SH-SY5Y cell lysate.
NLRP3 Ab
NLRP3 Ab
PM2.5 exposure impairs sperm quality through testicular damage dependent on NALP3 inflammasome and miR-183/96/182 cluster targeting FOXO1 in mouse. -Ecotoxicology and Environmental Safety
NLRP3 Ab
Kynurenic acid/GPR35 axis restricts NLRP3 inflammasome activation and exacerbates colitis in mice with social stress. -BRAIN BEHAVIOR AND IMMUNITY
NLRP3 Ab
Immunohistochemical analysis of paraffin-embedded human lung carcinoma, using NALP3 Antibody.

产品简介

Product Introduction

Catalog No.

CY5651

Source

Recombinant Rabbit mAb

UniProt ID

Q96P20

Reactivity

Human;Mouse;Rat

Application

WB;IHC;ICC/IF;IHF

Calculated Mol Weight

118 kDa

Observed Mol Weight

118 kDa

Recommended Dilution

WB 1:1000-1:2000

IHC 1:100-1:200

ICC/IF 1:50-1:200

IHF 1:50-1:200

Alternative Names

FCU; MWS; FCAS; Cias1; Mmig1; NLRP3; Pypaf1; AII/AVP; AGTAVPRL; Cryopyrin;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human NLRP3

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Sensor component of the NLRP3 inflammasome, which mediates inflammasome activation in response to defects in membrane integrity, leading to secretion of inflammatory cytokines IL1B and IL18 and pyroptosis.

引用文献

Citation

Sodium tanshinone IIA sulfonate ameliorates neointima by protecting endothelial progenitor cells in diabetic mice

期刊名称：

BMC Cardiovascular Disorders

PMID：

37697234

影响因子：

2.1

应用范围：

WB,ICC/IF,IP

检测物种：

Mouse

发表时间：

2023-09-11
Empagliflozin ameliorates vascular calcification in diabetic mice through inhibiting Bhlhe40-dependent NLRP3 inflammasome activation

期刊名称：

ACTA PHARMACOLOGICA SINICA

PMID：

38172306

影响因子：

6.9

应用范围：

ICC/IF

检测物种：

Mouse

发表时间：

2024-01-03
Intracellular and extracellular Cyclophilin a promote cardiac fibrosis through TGF-β signaling in response to angiotensin Ⅱ

期刊名称：

BIOCHEMICAL PHARMACOLOGY

PMID：

38723722

影响因子：

5.3

应用范围：

IHC,ICC/IF

检测物种：

Mouse

发表时间：

2024-05-07
FGF21 overexpression alleviates VSMC senescence in diabetic mice by modulating the SYK-NLRP3 inflammasome-PPARγ-catalase pathway: FGF21 alleviates high glucose-induced VSMC senescence

期刊名称：

ACTA BIOCHIMICA ET BIOPHYSICA SINICA

PMID：

38733164

影响因子：

3.3

应用范围：

ICC/IF,WB

检测物种：

Mouse

发表时间：

2024-05-10
A Novel Bifunctional Fusion Protein (Anti-IL-17A-sST2) Protects against Acute Liver Failure, Modulating the TLR4/MyD88 Pathway and NLRP3 Inflammasome Activation

期刊名称：

Biomedicines

PMID：

38791080

影响因子：

3.9

应用范围：

IHC

检测物种：

Mouse

发表时间：

2024-05-17
Multi-omics reveals the role of MCM2 and hnRNP K phosphorylation in mouse renal aging through genomic instability

期刊名称：

EXPERIMENTAL CELL RESEARCH

PMID：

38844260

影响因子：

3.3

应用范围：

WB

检测物种：

Mouse

发表时间：

2024-06-04

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CY5651

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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