PI3 kinase p85 alpha Ab
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PI3 kinase p85 alpha Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
PI3 kinase p85 alpha Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
PI3 kinase p85 alpha Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
PI3 kinase p85 alpha Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
PI3 kinase p85 alpha Ab
Western blot analysis of PI 3 Kinase p85 alpha expression in A431 cell lysate.
PI3 kinase p85 alpha Ab
PI3 kinase p85 alpha Ab
PI3 kinase p85 alpha Ab

产品简介

Product Introduction

Catalog No.

CY5355

Source

Recombinant Rabbit mAb

UniProt ID

P27986

Reactivity

Human;Mouse;Rat

Application

WB

Calculated Mol Weight

84 kDa

Observed Mol Weight

85 kDa

Recommended Dilution

WB 1:1000-1:2000

Alternative Names

GRB1; P85A; PI3-kinase p85-alpha; PI3K; PI3K p85-alpha; ptdIns-3-kinase p85-alpha;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human PI3 kinase p85 alpha

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling.

引用文献

Citation

Shexiang Tongxin Dropping Pill Promotes Angiogenesis through VEGF/eNOS Signaling Pathway on Diabetic Coronary Microcirculation Dysfunction

期刊名称：

Chinese Journal of Integrative Medicine

PMID：

38753274

影响因子：

2.2

应用范围：

WB

检测物种：

Mouse

发表时间：

2024-05-16
Oncogenic HPV-induced high expression of ESM1 predicts poor prognosis and regulates aerobic glycolysis in cervical cancer

期刊名称：

iScience

PMID：

38947495

影响因子：

4.6

应用范围：

WB

检测物种：

Human

发表时间：

2024-05-27
The resistance to anoikis, mediated by Spp1, and the evasion of immune surveillance facilitate the invasion and metastasis of hepatocellular carcinoma

期刊名称：

APOPTOSIS

PMID：

39066845

影响因子：

6.1

应用范围：

WB

检测物种：

Human

发表时间：

2024-07-27

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CY5355

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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