PI3 kinase p85 alpha Ab
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PI3 kinase p85 alpha Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
PI3 kinase p85 alpha Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
PI3 kinase p85 alpha Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
PI3 kinase p85 alpha Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
PI3 kinase p85 alpha Ab
Western blot analysis of PI 3 Kinase p85 alpha expression in A431 cell lysate.
PI3 kinase p85 alpha Ab
PI3 kinase p85 alpha Ab
PI3 kinase p85 alpha Ab

产品简介

Product Introduction

Catalog No.

CY5355

Source

Recombinant Rabbit mAb

UniProt ID

P27986

Reactivity

Human;Mouse;Rat

Application

WB

Calculated Mol Weight

84 kDa

Observed Mol Weight

85 kDa

Recommended Dilution

WB 1:1000-1:2000

Alternative Names

GRB1; P85A; PI3-kinase p85-alpha; PI3K; PI3K p85-alpha; ptdIns-3-kinase p85-alpha;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human PI3 kinase p85 alpha

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling.

引用文献

Citation

Atractylenolide-1 targets SPHK1 and B4GALT2 to regulate intestinal metabolism and flora composition to improve inflammation in mice with colitis

期刊名称：

PHYTOMEDICINE

PMID：

35114452

影响因子：

6.656

应用范围：

WB

检测物种：

Mouse

发表时间：

2022-01-15
Knockdown of DEAD-box 51 inhibits tumor growth of esophageal squamous cell carcinoma via the PI3K/AKT pathway

期刊名称：

WORLD JOURNAL OF GASTROENTEROLOGY

PMID：

35125830

影响因子：

5.374

应用范围：

WB

检测物种：

Human

发表时间：

2022-01-28
Syringin exerts anti-breast cancer effects through PI3K-AKT and EGFR-RAS-RAF pathways

期刊名称：

Journal of Translational Medicine

PMID：

35794555

影响因子：

8.44

应用范围：

WB

检测物种：

Human

发表时间：

2022-07-06
Compound 511 ameliorates MRSA-induced lung injury by attenuating morphine-induced immunosuppression in mice via PI3K/AKT/mTOR pathway

期刊名称：

PHYTOMEDICINE

PMID：

36252465

影响因子：

6.656

应用范围：

WB

检测物种：

Mouse

发表时间：

2022-09-25
N-linoleyltyrosine resisted the growth of non-small cell lung cancer cells via the regulation of CB1 and CB2 involvement of PI3K and ERK pathways

期刊名称：

Frontiers in Pharmacology

PMID：

37361232

影响因子：

5.6

应用范围：

ICC/IF,WB

检测物种：

Human

发表时间：

2023-06-08
Sophoridine Counteracts Obesity via Src-Mediated Inhibition of VEGFR Expression and PI3K/AKT Phosphorylation

期刊名称：

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

PMID：

38279206

影响因子：

4.9

应用范围：

WB

检测物种：

Mouse

发表时间：

2024-01-19

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CY5355

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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