INCENP Ab

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INCENP Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
INCENP Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
INCENP Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
INCENP Ab
INCENP Ab
INCENP Ab
INCENP Ab
INCENP Ab

产品简介

Product Introduction

Catalog No.

DY2160

Source

Recombinant Rabbit mAb

UniProt ID

Reactivity

Human;Mouse;Rat

Application

WB;IHC;ICC/IF;IP;FC

Calculated Mol Weight

105 kDa

Observed Mol Weight

140 kDa

Recommended Dilution

WB 1:1000-1:5000

IHC 1:100-1:200

ICC/IF 1:50-1:200

IP 1:20-1:50

FC 1:20-1:100

Alternative Names

Inner centromere protein

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Acts as a scaffold regulating CPC localization and activity. The C-terminus associates with AURKB or AURKC, the N-terminus associated with BIRC5/survivin and CDCA8/borealin tethers the CPC to the inner centromere, and the microtubule binding activity within the central SAH domain directs AURKB/C toward substrates near microtubules.

引用文献

Citation

No Data

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DY2160

Specifications:

50μl, 150μl

Price:

$188/50μl, $368/150μl

Delivery time:

1-4 weeks

Ordering information:

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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