UBA3 Ab
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UBA3 Ab
Western blot analysis of UBA3 expression in HeLa cell lysate.
UBA3 Ab
UBA3 Ab
UBA3 Ab
UBA3 Ab
UBA3 Ab
UBA3 Ab
UBA3 Ab

产品简介

Product Introduction

Catalog No.

DY1682

Source

Recombinant Rabbit mAb

UniProt ID

Q8TBC4

Reactivity

Human;Mouse;Rat

Application

WB

Calculated Mol Weight

52 kDa

Observed Mol Weight

52 kDa

Recommended Dilution

WB 1:1000-1:2000

Alternative Names

hUba3; NEDD8 activating enzyme E1C; uba3; UBE1C;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human UBA3

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Catalytic subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Down-regulates steroid receptor activity. Necessary for cell cycle progression.

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DY1682

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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