p-MCM2 (S27) Ab
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p-MCM2 (S27) Ab
Western blot analysis of Phospho-MCM2 (S27) expression in (1) HeLa cell lysate; (2) HeLa cell treated with alkaline phosphatase lysate.
p-MCM2 (S27) Ab
Immunoprecipitate (IP) analysis using the Antibody at 1:50 dilution. (wb at 1:1K dilution)
p-MCM2 (S27) Ab
p-MCM2 (S27) Ab
p-MCM2 (S27) Ab
p-MCM2 (S27) Ab
p-MCM2 (S27) Ab
p-MCM2 (S27) Ab

产品简介

Product Introduction

Catalog No.

DY1655

Source

Recombinant Rabbit mAb

UniProt ID

P49736

Reactivity

Human;Mouse;Rat

Application

WB;IHC;ICC/IF;IHF;IP

Calculated Mol Weight

102 kDa

Observed Mol Weight

125 kDa

Recommended Dilution

WB 1:1000-1:2000

IHC 1:100-1:200

ICC/IF 1:50-1:200

IHF 1:50-1:200

IP 1:20-1:50

Alternative Names

BM28; CCNL1; cdc19; CDCL1; Cyclin like 1; MCM2;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Phosphorylated

Immunogen

A synthesized peptide derived from human MCM2 around the phosphorylation site of S27

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Acts as a component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. Core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built.

引用文献

Citation

Multi-omics reveals the role of MCM2 and hnRNP K phosphorylation in mouse renal aging through genomic instability

期刊名称：

EXPERIMENTAL CELL RESEARCH

PMID：

38844260

影响因子：

3.3

应用范围：

WB

检测物种：

Mouse

发表时间：

2024-06-04

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DY1655

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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