HIF PH4 Ab
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HIF PH4 Ab
Western blot analysis of HIF Prolyl Hydroxylases expression in HeLa cell lysate.
HIF PH4 Ab
Immunoprecipitate (IP) analysis using the Antibody at 1:50 dilution. (wb at 1:1K dilution)
HIF PH4 Ab
HIF PH4 Ab
HIF PH4 Ab
HIF PH4 Ab
HIF PH4 Ab
HIF PH4 Ab

产品简介

Product Introduction

Catalog No.

DY1640

Source

Recombinant Rabbit mAb

UniProt ID

Q9NXG6

Reactivity

Human

Application

WB;IHC;IP;FC

Calculated Mol Weight

57 kDa

Observed Mol Weight

47 kDa

Recommended Dilution

WB 1:1000-1:2000

IHC 1:100-1:200

IP 1:20-1:50

FC 1:20-1:100

Alternative Names

EGLN4 ; HIFPH4; Hypoxia inducible factor prolyl 4 hydroxylase; P4H with transmembrane domain; P4htm; PH4; PHD4; Proline 4 hydroxylase; Prolyl hydroxlase domain containing 4;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human HIF PH4

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF1A at 'Pro-402' and 'Pro-564'. May function as a cellular oxygen sensor and, under normoxic conditions, may target HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex.

引用文献

Citation

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DY1640

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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