GRK6 Ab
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GRK6 Ab
Western blot analysis of GRK6 expression in Ramos cell lysate.
GRK6 Ab
GRK6 Ab
GRK6 Ab
GRK6 Ab
GRK6 Ab
GRK6 Ab
GRK6 Ab

产品简介

Product Introduction

Catalog No.

DY1621

Source

Recombinant Rabbit mAb

UniProt ID

P43250

Reactivity

Human;Mouse

Application

WB

Calculated Mol Weight

66 kDa

Observed Mol Weight

66 kDa

Recommended Dilution

WB 1:1000-1:2000

Alternative Names

G protein coupled receptor kinase 6; G protein coupled receptor kinase GRK6; G protein-coupled receptor kinase 6; Gprk6; Grk6;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human GRK6

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Specifically phosphorylates the activated forms of G protein-coupled receptors. Such receptor phosphorylation initiates beta-arrestin-mediated receptor desensitization, internalization, and signaling events leading to their desensitization. Seems to be involved in the desensitization of D2-like dopamine receptors in striatum and chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis.Phosphorylates rhodopsin (RHO) (in vitro) and a non G-protein-coupled receptor: LRP6 during Wnt signaling (in vitro).

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DY1621

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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