p62 SQSTM1 Ab
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p62 SQSTM1 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
p62 SQSTM1 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
p62 SQSTM1 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
p62 SQSTM1 Ab
Western blot analysis of SQSTM1 / p62 expression in HepG2 cell lysate.
p62 SQSTM1 Ab
Immunofluorescent analysis using the Antibody at 1:50 dilution.
p62 SQSTM1 Ab
Immunofluorescent analysis using the Antibody at 1:150 dilution.
p62 SQSTM1 Ab
Immunofluorescent analysis using the Antibody at 1:200 dilution.
p62 SQSTM1 Ab

产品简介

Product Introduction

Catalog No.

CY9081

Source

Recombinant Rabbit mAb

UniProt ID

Q13501

Reactivity

Human

Application

WB;IHC;ICC/IF;IHF;IP;FC

Calculated Mol Weight

48 kDa

Observed Mol Weight

62 kDa

Recommended Dilution

WB 1:1000-1:2000

IHC 1:100-1:200

ICC/IF 1:50-1:200

IHF 1:50-1:200

IP 1:20-1:50

FC 1:20-1:100

Alternative Names

A170; DMRV; EBIAP; ORCA; OSF-6; Osi; OSIL; p60; p62; p62B; PDB3; Sequestosome 1; Sqstm1; STAP; STONE14; Ubiquitin binding protein p62; ZIP; ZIP3;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human Sequestosome 1

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Molecular adapter required for selective macroautophagy (aggrephagy) by acting as a a bridge between polyubiquitinated proteins and autophagosomes.Promotes the recruitment of ubiquitinated cargo proteins to autophagosomes via multiple domains that bridge proteins and organelles in different steps.

引用文献

Citation

SUMOylation is enriched in the nuclear matrix and required for chromosome segregation

期刊名称：

JOURNAL OF BIOLOGICAL CHEMISTRY

PMID：

38072047

影响因子：

4.8

应用范围：

WB

检测物种：

Human

发表时间：

2023-12-10
Autophagic-lysosomal damage induced by swainsonine is protected by trehalose through activation of TFEB-regulated pathway in renal tubular epithelial cells

期刊名称：

CHEMICO-BIOLOGICAL INTERACTIONS

PMID：

38579922

影响因子：

4.7

应用范围：

WB

检测物种：

Rat

发表时间：

2024-04-03
MT1E in AML: A Gateway to Understanding Regulatory Cell Death and Immunotherapeutic Responses

期刊名称：

JOURNAL OF LEUKOCYTE BIOLOGY

PMID：

38943611

影响因子：

3.6

应用范围：

WB

检测物种：

Human

发表时间：

2024-06-29
A novel selective FAK inhibitor E2 inhibits ovarian cancer metastasis and growth by inducing cytotoxic autophagy

期刊名称：

BIOCHEMICAL PHARMACOLOGY

PMID：

39102992

影响因子：

5.3

应用范围：

WB

检测物种：

Mouse,Human

发表时间：

2024-08-03

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CY9081

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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