ERCC8 Ab
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ERCC8 Ab
Western blot analysis of ERCC8 expression in Molt4 cell lysate.
ERCC8 Ab
ERCC8 Ab
ERCC8 Ab
ERCC8 Ab
ERCC8 Ab
ERCC8 Ab
ERCC8 Ab

产品简介

Product Introduction

Catalog No.

CY8769

Source

Recombinant Rabbit mAb

UniProt ID

Q13216

Reactivity

Human

Application

WB;IP

Calculated Mol Weight

44 kDa

Observed Mol Weight

44 kDa

Recommended Dilution

WB 1:1000-1:2000

IP 1:20-1:50

Alternative Names

CKN1; CSA; ERCC8;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human ERCC8

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Substrate-recognition component of the CSA complex, a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex, involved in transcription-coupled nucleotide excision repair. The CSA complex (DCX(ERCC8) complex) promotes the ubiquitination and subsequent proteasomal degradation of ERCC6 in a UV-dependent manner; ERCC6 degradation is essential for the recovery of RNA synthesis after transcription-coupled repair.

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CY8769

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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