SRD5A2 Ab
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SRD5A2 Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
SRD5A2 Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
SRD5A2 Ab
Western blot analysis of SRD5A2 expression in PC3 cell lysate.
SRD5A2 Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
SRD5A2 Ab
SRD5A2 Ab
SRD5A2 Ab
SRD5A2 Ab

产品简介

Product Introduction

Catalog No.

CY8576

Source

Recombinant Rabbit mAb

UniProt ID

P31213

Reactivity

Human;Rat

Application

WB;IP

Calculated Mol Weight

28 kDa

Observed Mol Weight

28 kDa

Recommended Dilution

WB 1:1000-1:2000

IP 1:20-1:50

Alternative Names

SRD5A2; 5 alpha-SR2; S5AR 2; Type II 5-alpha reductase; SR type 2; Steroid 5-alpha-reductase 2;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human SRD5A2

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Converts testosterone (T) into 5-alpha-dihydrotestosterone (DHT) and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology.

引用文献

Citation

The antiandrogenic effect of neferine, liensinine, and isoliensinine by inhibiting 5-α-reductase and androgen receptor expression via PI3K/AKT signaling pathway in prostate cancer

期刊名称：

PHARMAZIE

PMID：

33964997

影响因子：

1.267

应用范围：

WB

检测物种：

Human

发表时间：

2021-05-01
Sinularin Exerts Anti-cancer Effects by Inducing Oxidative Stress-mediated Ferroptosis, Apoptosis, and Autophagy in Prostate Cancer Cells

期刊名称：

Anti-Cancer Agents in Medicinal Chemistry

PMID：

37005535

影响因子：

2.8

应用范围：

WB

检测物种：

Human

发表时间：

2023-07-01
Neferine attenuates development of testosterone-induced benign prostatic hyperplasia in mice by regulating androgen and TGF-β/Smad signaling pathways

期刊名称：

SAUDI PHARMACEUTICAL JOURNAL

PMID：

37293563

影响因子：

4.1

应用范围：

WB

检测物种：

Mouse

发表时间：

2023-05-11
Capsaicin reduces blood glucose and prevents prostate growth by regulating androgen, RAGE/IGF-1/Akt, TGF-β/Smad signalling pathway and reversing epithelial-mesenchymal transition in streptozotocin-induced diabetic mice

期刊名称：

NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

PMID：

38700794

影响因子：

3.1

应用范围：

WB

检测物种：

Mouse

发表时间：

2024-05-03

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CY8576

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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