CRK Ab
Instructions

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CRK Ab
Western blot analysis of CRKII expression in K562 cell lysate.
CRK Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
CRK Ab
Immunoprecipitate (IP) analysis using the Antibody at 1:50 dilution. (wb at 1:12K dilution)
CRK Ab
CRK Ab
CRK Ab
CRK Ab
CRK Ab
CRK Ab
CRK Ab
CRK Ab
CRK Ab

产品简介

Product Introduction

Catalog No.

CY8508

Source

Recombinant Rabbit mAb

UniProt ID

P46108

Reactivity

Human;Mouse;Rat

Application

WB;ICC/IF;IP;FC

Calculated Mol Weight

34 kDa

Observed Mol Weight

38 kDa

Recommended Dilution

WB 1:1000-1:2000

ICC/IF 1:50-1:200

IP 1:20-1:50

FC 1:20-1:100

Alternative Names

CRK; CRKII; p38;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human CRK

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

The Crk-I and Crk-II forms differ in their biological activities. Crk-II has less transforming activity than Crk-I. Crk-II mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. Involved in phagocytosis of apoptotic cells and cell motility via its interaction with DOCK1 and DOCK4. May regulate the EFNA5-EPHA3 signaling.

引用文献

Citation

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CY8508

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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>> All rabbit monoclonal antibody products targeting this target