SMG1 Ab
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SMG1 Ab
Western blot analysis of Smg1 expression in Saos2 cell lysate.
SMG1 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
SMG1 Ab
SMG1 Ab
SMG1 Ab
SMG1 Ab
SMG1 Ab
SMG1 Ab
SMG1 Ab
SMG1 Ab
SMG1 Ab
SMG1 Ab

产品简介

Product Introduction

Catalog No.

CY8486

Source

Recombinant Rabbit mAb

UniProt ID

Q96Q15

Reactivity

Human;Mouse;Rat

Application

WB

Calculated Mol Weight

411 kDa

Observed Mol Weight

410 kDa

Recommended Dilution

WB 1:1000-1:2000

Alternative Names

61E3.4; ATX; hSMG1; LIP; smg1;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human SMG1

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Serine/threonine protein kinase involved in both mRNA surveillance and genotoxic stress response pathways. Recognizes the substrate consensus sequence [ST]-Q. Plays a central role in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons by phosphorylating UPF1/RENT1. Recruited by release factors to stalled ribosomes together with SMG8 and SMG9 (forming the SMG1C protein kinase complex), and UPF1 to form the transient SURF (SMG1-UPF1-eRF1-eRF3) complex.

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CY8486

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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