REST corepressor 1 Ab

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REST corepressor 1 Ab
Western blot analysis of CoREST expression in Molt-4 cell lysate.
REST corepressor 1 Ab
REST corepressor 1 Ab
REST corepressor 1 Ab
REST corepressor 1 Ab
REST corepressor 1 Ab
REST corepressor 1 Ab
REST corepressor 1 Ab

产品简介

Product Introduction

Catalog No.

CY8197

Source

Recombinant Rabbit mAb

UniProt ID

Reactivity

Human;Mouse;Rat

Application

WB;IHC;ICC/IF;IHF

Calculated Mol Weight

53 kDa

Observed Mol Weight

66 kDa

Recommended Dilution

WB 1:1000-1:2000

IHC 1:100-1:200

ICC/IF 1:50-1:200

IHF 1:50-1:200

Alternative Names

COREST; Nr2b2; RCOR; Rcor1; Rxrb;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Essential component of the BHC complex, a corepressor complex that represses transcription of neuron-specific genes in non-neuronal cells. The BHC complex is recruited at RE1/NRSE sites by REST and acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier. In the BHC complex, it serves as a molecular beacon for the recruitment of molecular machinery, including MeCP2 and SUV39H1, that imposes silencing across a chromosomal interval.

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CY8197

Specifications:

50μl, 150μl

Price:

$188/50μl, $368/150μl

Delivery time:

1-4 weeks

Ordering information:

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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