E2AK3 Ab
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E2AK3 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
E2AK3 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
E2AK3 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
E2AK3 Ab
E2AK3 Ab
E2AK3 Ab
E2AK3 Ab
E2AK3 Ab
E2AK3 Ab
E2AK3 Ab
E2AK3 Ab
E2AK3 Ab

产品简介

Product Introduction

Catalog No.

CY7606

Source

Recombinant Rabbit mAb

UniProt ID

Q9NZJ5

Reactivity

Human;Mouse;Rat

Application

WB

Calculated Mol Weight

125 kDa

Observed Mol Weight

140 kDa

Recommended Dilution

WB 1:1000-1:2000(Tissue sample) 1:5000-10000(Cell sample)

Alternative Names

EIF2AK3; PEK ;PERK; Pancreatic eIF2-alpha kinase; HsPEK; Pancreatic eIF2-alpha kinase; Protein tyrosine kinase EIF2AK3; Pancreatic eIF2-alpha kinase; Eukaryotic translation initiation factor 2-alpha kinase 3;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human E2AK3

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Metabolic-stress sensing protein kinase that phosphorylates the alpha subunit of eukaryotic translation initiation factor 2 (EIF2S1/eIF-2-alpha) in response to various stress, such as unfolded protein response (UPR).Key effector of the integrated stress response (ISR) to unfolded proteins: EIF2AK3/PERK specifically recognizes and binds misfolded proteins, leading to its activation and EIF2S1/eIF-2-alpha phosphorylation.

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CY7606

Specifications：

50μl, 145μl

Price：

$188/50μl, $368/145μl

Delivery time：

1-1 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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>> All rabbit monoclonal antibody products targeting this target