METTL3 Ab
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METTL3 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
METTL3 Ab
Western blot analysis of METTL3 expression in (1) 293 cell lysate; (2) RAW 264.7 cell lysate.
METTL3 Ab
METTL3 Ab
METTL3 Ab
METTL3 Ab
METTL3 Ab
METTL3 Ab

产品简介

Product Introduction

Catalog No.

CY7240

Source

Recombinant Rabbit mAb

UniProt ID

Q86U44

Reactivity

Human;Mouse;Rat

Application

WB;IHC;ICC/IF;IHF;IP;FC

Calculated Mol Weight

64 kDa

Observed Mol Weight

70 kDa

Recommended Dilution

WB 1:1000-1:2000

IHC 1:100-1:200

ICC/IF 1:50-1:200

IHF 1:50-1:200

IP 1:20-1:50

FC 1:20-1:100

Alternative Names

IME4; M6A; Methyltransferase like protein 3; METTL3; MTA70; N6 adenosine methyltransferase 70 kDa subunit;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human METTL3

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

The METTL3-METTL14 heterodimer forms a N6-methyltransferase complex that methylates adenosine residues at the N6 position of some RNAs and regulates various processes such as the circadian clock, differentiation of embryonic and hematopoietic stem cells, cortical neurogenesis, response to DNA damage, differentiation of T-cells and primary miRNA processing.

引用文献

Citation

METTL3 promotes proliferation and myogenic differentiation through m6A RNA methylation/YTHDF1/2 signaling axis in myoblasts

期刊名称：

LIFE SCIENCES

PMID：

35351467

影响因子：

6.78

应用范围：

WB

检测物种：

Mouse

发表时间：

2022-03-26
METTL14 depletion induces trophoblast cell dysfunction by inhibiting miR–21-5p processing in an m6A-dependent manner

期刊名称：

INTERNATIONAL IMMUNOPHARMACOLOGY

PMID：

39332090

影响因子：

4.8

应用范围：

WB

检测物种：

Human

发表时间：

2024-09-27

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CY7240

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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