p-ERK1/2 (T202/T185) Ab
Instructions

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p-ERK1/2 (T202/T185) Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
p-ERK1/2 (T202/T185) Ab
Western blot analysis of Phospho-ERK1 (T202) + ERK2 (T185) expression in (1) NIH/3T3 cell lysate; (2) NIH/3T3 cell lysate treated with PDGF.
p-ERK1/2 (T202/T185) Ab
Immunofluorescent analysis using the Antibody at 1:50 dilution.
p-ERK1/2 (T202/T185) Ab
Immunofluorescent analysis using the Antibody at 1:150 dilution.
p-ERK1/2 (T202/T185) Ab
p-ERK1/2 (T202/T185) Ab
p-ERK1/2 (T202/T185) Ab
p-ERK1/2 (T202/T185) Ab

产品简介

Product Introduction

Catalog No.

CY7165

Source

Recombinant Rabbit mAb

UniProt ID

P27361/P28482

Reactivity

Human;Mouse;Rat

Application

WB;IHC;ICC/IF;IHF;IP

Calculated Mol Weight

43,41 kDa

Observed Mol Weight

42, 44 kDa

Recommended Dilution

WB 1:1000-1:2000

IHC 1:100-1:200

ICC/IF 1:50-1:200

IHF 1:50-1:200

IP 1:20-1:50

Alternative Names

MAPK3; MK03; MNK1; p44-ERK1; P44-ER; ERK-1; ERK1; ERT2; kinase ERK1; MAP kinase 1; MAPK 1;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Phosphorylated

Immunogen

A synthesized peptide derived from human ERK1 around the phosphorylation site of T202

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements.

引用文献

Citation

Phenols fragment of Veronica ciliata Fisch. ameliorate free radical-induced nonalcoholic fatty liver disease by mediating PI3K/Akt signaling pathway

期刊名称：

JOURNAL OF ETHNOPHARMACOLOGY

PMID：

31978521

影响因子：

3.69

应用范围：

WB

检测物种：

Rat

发表时间：

2020-01-21
Demethoxycurcumin analogue DMC-BH inhibits orthotopic growth of glioma stem cells by targeting JNK/ERK signaling

期刊名称：

Aging-US

PMID：

32710727

影响因子：

4.831

应用范围：

WB

检测物种：

Human

发表时间：

2020-07-24
Chaetoglobosin E inhibits tumor growth and promotes the anti-tumor efficacy of cytotoxic drugs in esophageal squamous cell carcinoma by targeting PLK1

期刊名称：

Annals of Translational Medicine

PMID：

36544631

影响因子：

3.616

应用范围：

WB

检测物种：

Human

发表时间：

2022-11-01
Niclosamide modulates phenotypic switch and inflammatory responses in human pulmonary arterial smooth muscle cells

期刊名称：

MOLECULAR AND CELLULAR BIOCHEMISTRY

PMID：

38980591

影响因子：

3.5

应用范围：

WB

检测物种：

Human

发表时间：

2024-07-09

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CY7165

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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