TRPM7 Ab
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TRPM7 Ab
Western blot analysis of TRPM7 expression in HeLa cell lysate.
TRPM7 Ab
TRPM7 Ab
TRPM7 Ab
TRPM7 Ab
TRPM7 Ab
TRPM7 Ab
TRPM7 Ab

产品简介

Product Introduction

Catalog No.

CY7162

Source

Recombinant Rabbit mAb

UniProt ID

Q96QT4

Reactivity

Human;Mouse;Rat

Application

WB;ICC/IF;FC

Calculated Mol Weight

213 kDa

Observed Mol Weight

213 kDa

Recommended Dilution

WB 1:1000-1:2000

ICC/IF 1:50-1:200

FC 1:20-1:100

Alternative Names

ALSPDC; CHAK; CHAK1; LTrpC7; TRPM7;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human TRPM7

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Essential ion channel and serine/threonine-protein kinase. Divalent cation channel permeable to calcium and magnesium.Has a central role in magnesium ion homeostasis and in the regulation of anoxic neuronal cell death. Involved in TNF-induced necroptosis downstream of MLKL by mediating calcium influx. The kinase activity is essential for the channel function. May be involved in a fundamental process that adjusts plasma membrane divalent cation fluxes according to the metabolic state of the cell. Phosphorylates annexin A1 (ANXA1).

引用文献

Citation

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CY7162

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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