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Product Introduction
Catalog No.
Source
UniProt ID
Reactivity
Application
Calculated Mol Weight
Observed Mol Weight
Recommended Dilution
WB 1:1000-1:2000
IHC 1:100-1:200
ICC/IF 1:50-1:200
IHF 1:50-1:200
FC 1:20-1:100
Alternative Names
SH2 domain protein C1; SHC; SHC-transforming protein 1; SHCA; Src homology 2 domain-containing-transforming protein C1;
Host
Isotype
Clonality
Modification
Immunogen
Purification
Concentration
Buffer System
Storage Condition
Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.
Description
Shc1 IS an adaptor protein containing a SH2 domain and a PID domain within a PH domain-like fold. Three isoforms(p66, p52 and p46), produced by alternative initiation, variously regulate growth factor signaling, oncogenesis and apoptosis.
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