TRIM25 Ab
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TRIM25 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
TRIM25 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
TRIM25 Ab
Western blot analysis of TRIM25 expression in HeLa cell lysate.
TRIM25 Ab
TRIM25 Ab
TRIM25 Ab
TRIM25 Ab
TRIM25 Ab

产品简介

Product Introduction

Catalog No.

CY7155

Source

Recombinant Rabbit mAb

UniProt ID

Q14258

Reactivity

Human;Mouse;Rat

Application

WB;IHC;ICC/IF;IHF;IP;FC

Calculated Mol Weight

71 kDa

Observed Mol Weight

71 kDa

Recommended Dilution

WB 1:1000-1:2000

IHC 1:100-1:200

ICC/IF 1:50-1:200

IHF 1:50-1:200

IP 1:20-1:50

FC 1:20-1:100

Alternative Names

EFP; RNF147; TRI25; TRIM 25; Trim25; Z147; ZNF147;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human TRIM25

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Functions as an ubiquitin E3 ligase and as an ISG15 E3 ligase. Involved in innate immune defense against viruses by mediating ubiquitination of DDX58. Mediates 'Lys-63'-linked polyubiquitination of the DDX58 N-terminal CARD-like region which is crucial for triggering the cytosolic signal transduction that leads to the production of interferons in response to viral infection.

引用文献

Citation

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CY7155

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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