PHF8 Ab
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PHF8 Ab
Western blot analysis of PHF8 expression in (1) Jurkat cell lysate; (2) NIH/3T3 cell lysate.
PHF8 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
PHF8 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
PHF8 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
PHF8 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
PHF8 Ab
PHF8 Ab
PHF8 Ab
PHF8 Ab
PHF8 Ab
PHF8 Ab
PHF8 Ab

产品简介

Product Introduction

Catalog No.

CY7098

Source

Recombinant Rabbit mAb

UniProt ID

Q9UPP1

Reactivity

Human;Mouse;Rat

Application

WB;ICC/IF;IP

Calculated Mol Weight

118 kDa

Observed Mol Weight

140 kDa

Recommended Dilution

WB 1:1000-1:2000

ICC/IF 1:50-1:200

IP 1:20-1:50

Alternative Names

Histone lysine demethylase PHF8; MRXSSD; PHD finger protein 8; PHF8; ZNF422;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human PHF8

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Histone lysine demethylase with selectivity for the di- and monomethyl states that plays a key role cell cycle progression, rDNA transcription and brain development. Demethylates mono- and dimethylated histone H3 'Lys-9' residue (H3K9Me1 and H3K9Me2), dimethylated H3 'Lys-27' (H3K27Me2) and monomethylated histone H4 'Lys-20' residue (H4K20Me1). Acts as a transcription activator as H3K9Me1, H3K9Me2, H3K27Me2 and H4K20Me1 are epigenetic repressive marks. Involved in cell cycle progression by being required to control G1-S transition.

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CY7098

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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