PHF8 Ab
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PHF8 Ab
Western blot analysis of PHF8 expression in (1) Jurkat cell lysate; (2) NIH/3T3 cell lysate.
PHF8 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
PHF8 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
PHF8 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
PHF8 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
PHF8 Ab
PHF8 Ab
PHF8 Ab

产品简介

Product Introduction

Catalog No.

CY7098

Source

Recombinant Rabbit mAb

UniProt ID

Q9UPP1

Reactivity

Human;Mouse;Rat

Application

WB;ICC/IF;IP

Calculated Mol Weight

118 kDa

Observed Mol Weight

140 kDa

Recommended Dilution

WB 1:1000-1:2000

ICC/IF 1:50-1:200

IP 1:20-1:50

Alternative Names

Histone lysine demethylase PHF8; MRXSSD; PHD finger protein 8; PHF8; ZNF422;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human PHF8

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Histone lysine demethylase with selectivity for the di- and monomethyl states that plays a key role cell cycle progression, rDNA transcription and brain development. Demethylates mono- and dimethylated histone H3 'Lys-9' residue (H3K9Me1 and H3K9Me2), dimethylated H3 'Lys-27' (H3K27Me2) and monomethylated histone H4 'Lys-20' residue (H4K20Me1). Acts as a transcription activator as H3K9Me1, H3K9Me2, H3K27Me2 and H4K20Me1 are epigenetic repressive marks. Involved in cell cycle progression by being required to control G1-S transition.

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CY7098

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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