ISG15 Ab
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ISG15 Ab
Western blot analysis of ISG15 expression in Hela cell lysate treated with IFN α.
ISG15 Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
ISG15 Ab
ISG15 Ab
ISG15 Ab
ISG15 Ab
ISG15 Ab
ISG15 Ab

产品简介

Product Introduction

Catalog No.

CY7086

Source

Recombinant Rabbit mAb

UniProt ID

P05161

Reactivity

Human

Application

WB;IHC;ICC/IF;IHF

Calculated Mol Weight

18 kDa

Observed Mol Weight

15 kDa

Recommended Dilution

WB 1:1000-1:2000

IHC 1:100-1:200

ICC/IF 1:50-1:200

IHF 1:50-1:200

Alternative Names

IP17; Ubiquitin cross-reactive protein; hUCRP; ISG15; G1P2;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human ISG15

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Ubiquitin-like protein which plays a key role in the innate immune response to viral infection either via its conjugation to a target protein (ISGylation) or via its action as a free or unconjugated protein. ISGylation involves a cascade of enzymatic reactions involving E1, E2, and E3 enzymes which catalyze the conjugation of ISG15 to a lysine residue in the target protein.

引用文献

Citation

SARS-CoV-2 ORF10 suppresses the antiviral innate immune response by degrading MAVS through mitophagy

期刊名称：

Cellular & Molecular Immunology

PMID：

34845370

影响因子：

11.53

应用范围：

WB

检测物种：

Human

发表时间：

2021-11-29

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CY7086

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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