PDK1 Ab
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PDK1 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
PDK1 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
PDK1 Ab
Western blot analysis of PDK1 expression in LNCaP cell lysate.
PDK1 Ab
PDK1 Ab
PDK1 Ab
PDK1 Ab
PDK1 Ab

产品简介

Product Introduction

Catalog No.

CY6926

Source

Recombinant Rabbit mAb

UniProt ID

Q15118

Reactivity

Human;Mouse;Rat

Application

WB;IP

Calculated Mol Weight

49 kDa

Observed Mol Weight

49 kDa

Recommended Dilution

WB 1:1000-1:2000

IP 1:20-1:50

Alternative Names

Mitochondrial pyruvate dehydrogenase kinase isoenzyme 1; PDH kinase 1; Pdk1; Pyruvate dehydrogenase kinase isoform 1; Pyruvate dehydrogenase kinase, isoenzyme 1;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human PDK1

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Kinase that plays a key role in regulation of glucose and fatty acid metabolism and homeostasis via phosphorylation of the pyruvate dehydrogenase subunits PDHA1 and PDHA2. This inhibits pyruvate dehydrogenase activity, and thereby regulates metabolite flux through the tricarboxylic acid cycle, down-regulates aerobic respiration and inhibits the formation of acetyl-coenzyme A from pyruvate.

引用文献

Citation

Fibulin-3 Has Anti-Tumorigenic Activities in Cutaneous Squamous Cell Carcinoma

期刊名称：

JOURNAL OF INVESTIGATIVE DERMATOLOGY

PMID：

30738056

影响因子：

6.29

应用范围：

WB

检测物种：

Mouse,Human

发表时间：

2019-02-06
Pyruvate-Enriched Oral Rehydration Solution Improves Glucometabolic Disorders in the Kidneys of Diabetic db/db Mice

期刊名称：

Journal of Diabetes Research

PMID：

33062708

影响因子：

2.965

应用范围：

WB

检测物种：

Mouse

发表时间：

2020-09-25

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CY6926

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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