IRAK1 Ab
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IRAK1 Ab
IRAK1 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
IRAK1 Ab
Immunofluorescent analysis using the Antibody at 1:50 dilution.
IRAK1 Ab
IRAK1 Ab
IRAK1 Ab
IRAK1 Ab
IRAK1 Ab
IRAK1 Ab
IRAK1 Ab
IRAK1 Ab
IRAK1 Ab

产品简介

Product Introduction

Catalog No.

CY6917

Source

Recombinant Rabbit mAb

UniProt ID

P51617

Reactivity

Human

Application

WB;ICC/IF;IP

Calculated Mol Weight

77 kDa

Observed Mol Weight

77 kDa

Recommended Dilution

WB 1:1000-1:2000

ICC/IF 1:50-1:200

IP 1:20-1:50

Alternative Names

Il1rak; IRAK; Irak1; IRAK1-S; mPLK; Pelle; Pelle homolog; Pelle-like protein kinase; Plpk;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human IRAK1

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Serine/threonine-protein kinase that plays a critical role in initiating innate immune response against foreign pathogens. Involved in Toll-like receptor (TLR) and IL-1R signaling pathways. Is rapidly recruited by MYD88 to the receptor-signaling complex upon TLR activation. Association with MYD88 leads to IRAK1 phosphorylation by IRAK4 and subsequent autophosphorylation and kinase activation.

引用文献

Citation

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CY6917

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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