PI3 kinase p85 alpha Ab
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PI3 kinase p85 alpha Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
PI3 kinase p85 alpha Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
PI3 kinase p85 alpha Ab
Western blot analysis of PI3 Kinase p85 alpha expression in (1) K562 cell lysate; (2) Raw 264.7 cell lysate; (3) C6 cell lysate.
PI3 kinase p85 alpha Ab
LncRNA AK023391 promotes tumorigenesis and invasion of gastric cancer through activation of the PI3K/Akt signaling pathway. -Journal of Experimental & Clinical Cancer Research
PI3 kinase p85 alpha Ab
Immunofluorescent analysis using the Antibody at 1:50 dilution.
PI3 kinase p85 alpha Ab
Immunofluorescent analysis using the Antibody at 1:150 dilution.
PI3 kinase p85 alpha Ab
PI3 kinase p85 alpha Ab

产品简介

Product Introduction

Catalog No.

CY6915

Source

Recombinant Rabbit mAb

UniProt ID

P27986

Reactivity

Human;Mouse;Rat

Application

WB;ICC/IF

Calculated Mol Weight

84 kDa

Observed Mol Weight

83 kDa

Recommended Dilution

WB 1:1000-1:2000

ICC/IF 1:50-1:200

Alternative Names

GRB1; p85 alpha; PI3-kinase subunit p85-alpha; PI3K; PI3K regulatory subunit alpha; Pik3r1; PtdIns 3 kinase p85 alpha;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human PI3 kinase p85 alpha

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling.

引用文献

Citation

Salidroside induces apoptosis and protective autophagy in human gastric cancer AGS cells through the PI3K/Akt/mTOR pathway

期刊名称：

BIOMEDICINE & PHARMACOTHERAPY

PMID：

31918283

影响因子：

3.743

应用范围：

WB

检测物种：

Human

发表时间：

2019-12-30
Phenols fragment of Veronica ciliata Fisch. ameliorate free radical-induced nonalcoholic fatty liver disease by mediating PI3K/Akt signaling pathway

期刊名称：

JOURNAL OF ETHNOPHARMACOLOGY

PMID：

31978521

影响因子：

3.69

应用范围：

WB

检测物种：

Rat

发表时间：

2020-01-21
Progesterone attenuates Aβ25–35-induced neuronal toxicity by activating the Ras signalling pathway through progesterone receptor membrane component 1

期刊名称：

LIFE SCIENCES

PMID：

32001269

影响因子：

3.647

应用范围：

WB

检测物种：

Rat

发表时间：

2020-01-27
Peroxisomal proliferator-activated receptor α-b deficiency induces the reprogramming of nutrient metabolism in zebrafish

期刊名称：

JOURNAL OF PHYSIOLOGY-LONDON

PMID：

32710562

影响因子：

4.547

应用范围：

WB

检测物种：

Zebrafish

发表时间：

2020-07-25
CircRNA8220 Sponges MiR-8516 to Regulate Cell Viability and Milk Synthesis via Ras/MEK/ERK and PI3K/AKT/mTOR Pathways in Goat Mammary Epithelial Cells

期刊名称：

Animals

PMID：

32759741

影响因子：

2.323

应用范围：

WB

检测物种：

Goat

发表时间：

2020-08-04
The reduction of lipid-sourced energy production caused by ATGL inhibition cannot be compensated by activation of HSL, autophagy, and utilization of other nutrients in fish

期刊名称：

FISH PHYSIOLOGY AND BIOCHEMISTRY

PMID：

33245450

影响因子：

2.249

应用范围：

WB

检测物种：

Zebrafish

发表时间：

2020-11-27

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CY6915

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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