NR5A2 Ab
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NR5A2 Ab
Western blot analysis of NR5A2 expression in MCF7 cell lysate.
NR5A2 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
NR5A2 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
NR5A2 Ab
NR5A2 Ab
NR5A2 Ab
NR5A2 Ab
NR5A2 Ab

产品简介

Product Introduction

Catalog No.

CY6894

Source

Recombinant Rabbit mAb

UniProt ID

O00482

Reactivity

Human;Mouse;Rat

Application

WB

Calculated Mol Weight

61 kDa

Observed Mol Weight

70 kDa

Recommended Dilution

WB 1:1000-1:2000

Alternative Names

B1-binding factor; B1F2; CPF; CYP7A promoter-binding factor; FTF; FTZ F1; FTZ F1beta; FTZ-F1; FTZ-F1beta; hB1F 2; hB1F-2; LRH1; Nr5a2;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human NR5A2

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Nuclear receptor that acts as a key metabolic sensor by regulating the expression of genes involved in bile acid synthesis, cholesterol homeostasis and triglyceride synthesis. Together with the oxysterol receptors NR1H3/LXR-alpha and NR1H2/LXR-beta, acts as an essential transcriptional regulator of lipid metabolism. Plays an anti-inflammatory role during the hepatic acute phase response by acting as a corepressor: inhibits the hepatic acute phase response by preventing dissociation of the N-Cor corepressor complex.

引用文献

Citation

Dihydroartemisinin promoted FXR expression independent of YAP1 in hepatocellular carcinoma

期刊名称：

FASEB JOURNAL

PMID：

35616366

影响因子：

5.834

应用范围：

WB

检测物种：

Human

发表时间：

2022-05-26

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CY6894

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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