Integrin alpha V Ab
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Integrin alpha V Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
Integrin alpha V Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
Integrin alpha V Ab
Western blot analysis of Integrin alpha V expression in (1) A549 cell lysate; (2) Mouse spleen lysate; (3) Rat brain lysate.
Integrin alpha V Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
Integrin alpha V Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
Integrin alpha V Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
Integrin alpha V Ab
Immunofluorescent analysis using the Antibody at 1:50 dilution.
Integrin alpha V Ab
Immunofluorescent analysis using the Antibody at 1:50 dilution.

产品简介

Product Introduction

Catalog No.

CY6887

Source

Recombinant Rabbit mAb

UniProt ID

P06756

Reactivity

Human;Mouse;Rat

Application

WB;IHC;ICC/IF;IHF;IP

Calculated Mol Weight

116 kDa

Observed Mol Weight

125, 135 kDa

Recommended Dilution

WB 1:1000-1:2000

IHC 1:100-1:200

ICC/IF 1:50-1:200

IHF 1:50-1:200

IP 1:20-1:50

Alternative Names

CD51; Integrin alpha five; integrin alpha V beta 3; Integrin alpha-V light chain; ITGAV; Msk8;Vitronectin receptor subunit alpha; VNRA; VTNR;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human Integrin alpha V

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. ITGAV:ITGB3 binds to fractalkine (CX3CL1) and may act as its coreceptor in CX3CR1-dependent fractalkine signaling.

引用文献

Citation

Synergistic cytotoxicity and co-autophagy inhibition in pancreatic tumor cells and cancer-associated fibroblasts by dual functional peptide-modified liposomes

期刊名称：

Acta Biomaterialia

PMID：

31499197

影响因子：

6.638

应用范围：

WB

检测物种：

Mouse,Human

发表时间：

2019-09-06
IntegrinB5 upregulated by HER2 in gastric cancer: a promising biomarker for liver metastasis

期刊名称：

Annals of Translational Medicine

PMID：

32395495

影响因子：

3.297

应用范围：

IHC

检测物种：

Human

发表时间：

2020-04-01

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CY6887

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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