ADAM 17 Ab
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ADAM 17 Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
ADAM 17 Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
ADAM 17 Ab
Western blot analysis of ADAM17 expression in Hela cell lysate.
ADAM 17 Ab
Immunofluorescent analysis using the Antibody at 1:50 dilution.
ADAM 17 Ab
Immunofluorescent analysis using the Antibody at 1:200 dilution.
ADAM 17 Ab
Immunofluorescent analysis of Hela cells, using ADAM17 Antibody.
ADAM 17 Ab
ADAM 17 Ab

产品简介

Product Introduction

Catalog No.

CY6698

Source

Recombinant Rabbit mAb

UniProt ID

P78536

Reactivity

Human;Mouse;Rat

Application

WB;ICC/IF;IP;FC

Calculated Mol Weight

93 kDa

Observed Mol Weight

100 kDa

Recommended Dilution

WB 1:1000-1:2000

ICC/IF 1:50-1:200

IP 1:20-1:50

FC 1:20-1:100

Alternative Names

CD156b; ADAM17; CSVP; TACE;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human ADAM 17

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

TACE is responsible for the shedding of EGFR ligands such as amphiregulin and TNF-α. Some tumors have hyperactivated EGFR due to upregulated TNF-α production and upregulated TACE, making TACE a potential target for drug development. TACE activates Notch in a ligand-independent manner and has been shown to play a role in the development of the Drosophila nervous system.

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CY6698

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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