TP53BP2 Ab
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TP53BP2 Ab
Western blot analysis of ASPP2 expression in MCF7 cell lysate.
TP53BP2 Ab
All lanes use the Antibody at 1:2k dilution for 1 hour at room temperature.
TP53BP2 Ab
All lanes use the Antibody at 1:2k dilution for 1 hour at room temperature.
TP53BP2 Ab
All lanes use the Antibody at 1:2k dilution for 1 hour at room temperature.
TP53BP2 Ab
TP53BP2 Ab
TP53BP2 Ab
TP53BP2 Ab

产品简介

Product Introduction

Catalog No.

CY6658

Source

Recombinant Rabbit mAb

UniProt ID

Q13625

Reactivity

Human

Application

WB;IHC;ICC/IF;IHF

Calculated Mol Weight

126 kDa

Observed Mol Weight

150 kDa

Recommended Dilution

WB 1:1000-1:2000

IHC 1:100-1:200

ICC/IF 1:50-1:200

IHF 1:50-1:200

Alternative Names

53BP2; ASPP2; p53BP2; PPP1R13A; Tp53bp2;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human TP53BP2

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Regulator that plays a central role in regulation of apoptosis and cell growth via its interactions. Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo. Inhibits the ability of APPBP1 to conjugate NEDD8 to CUL1, and thereby decreases APPBP1 ability to induce apoptosis. Impedes cell cycle progression at G2/M. Its apoptosis-stimulating activity is inhibited by its interaction with DDX42.

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CY6658

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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