DNMT1 Ab
Instructions

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DNMT1 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
DNMT1 Ab
Western blot analysis of Dnmt1 expression in (1) HEK293 cell lysate; (2) NIH/3T3 cell lysate.
DNMT1 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
DNMT1 Ab
Immunohistochemical analysis of paraffin-embedded Rat spleen, using the Antibody at 1:100 dilution.
DNMT1 Ab
Immunohistochemical analysis of paraffin-embedded Human lung large cell cancer, using the Antibody at 1:100 dilution.
DNMT1 Ab
Immunohistochemical analysis of paraffin-embedded Human glioblastoma, using the Antibody at 1:100 dilution.
DNMT1 Ab
Immunohistochemical analysis of paraffin-embedded Mouse lung, using the Antibody at 1:100 dilution.
DNMT1 Ab

产品简介

Product Introduction

Catalog No.

CY6649

Source

Recombinant Rabbit mAb

UniProt ID

P26358

Reactivity

Human;Mouse;Rat

Application

WB;IHC;ICC/IF;IHF

Calculated Mol Weight

183 kDa

Observed Mol Weight

183 kDa

Recommended Dilution

WB 1:1000-1:2000

IHC 1:100-1:200

ICC/IF 1:50-1:200

IHF 1:50-1:200

Alternative Names

ADCADN; CXXC finger protein 9; CXXC9; DNA methyltransferase 1; DNA MTase; Dnmt1o; HSN1E; M.HsaI; MCMT; Met1; MommeD2;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human DNMT1

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Methylation of DNA at cytosine residues in mammalian cells is a heritable, epigenetic modification that is critical for proper regulation of gene expression, genomic imprinting and development. It is responsible for maintaining methylation patterns established in development. DNA methylation is coordinated with methylation of histones. Mediates transcriptional repression by direct binding to HDAC2.

引用文献

Citation

Nuclear UHRF1 is a gate-keeper of cellular AMPK activity and function

期刊名称：

CELL RESEARCH

PMID：

34561619

影响因子：

25.617

应用范围：

WB,IP

检测物种：

Human,Mouse

发表时间：

2021-09-24

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CY6649

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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