p-PKC alpha (T638) Ab
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p-PKC alpha (T638) Ab
Western blot analysis of Phospho-PKC alpha (T638) expression in (1) Jurkat cell lysate treated with TPA; (2) Jurkat cell lysate.
p-PKC alpha (T638) Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
p-PKC alpha (T638) Ab
p-PKC alpha (T638) Ab
p-PKC alpha (T638) Ab
p-PKC alpha (T638) Ab
p-PKC alpha (T638) Ab
p-PKC alpha (T638) Ab

产品简介

Product Introduction

Catalog No.

CY6628

Source

Recombinant Rabbit mAb

UniProt ID

P17252

Reactivity

Human;Mouse;Rat

Application

WB;IHC;ICC/IF;IHF;IP

Calculated Mol Weight

77 kDa

Observed Mol Weight

80 kDa

Recommended Dilution

WB 1:1000-1:2000

IHC 1:100-1:200

ICC/IF 1:50-1:200

IHF 1:50-1:200

IP 1:20-1:50

Alternative Names

EC 2.7.11.13; KPCA; PKC III; PKC-A; PKC-III; PKC-alpha; PRKACA; PRKCA; Protein kinase C; alpha type; kinase PKC-alpha;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Phosphorylated

Immunogen

A synthesized peptide derived from human PKC alpha around the phosphorylation site of T638

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Calcium-activated, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that is involved in positive and negative regulation of cell proliferation, apoptosis, differentiation, migration and adhesion, tumorigenesis, cardiac hypertrophy, angiogenesis, platelet function and inflammation, by directly phosphorylating targets such as RAF1, BCL2, CSPG4, TNNT2/CTNT, or activating signaling cascade involving MAPK1/3 (ERK1/2) and RAP1GAP.

引用文献

Citation

Vascular endothelial growth factor increases the function of calcium-impermeable AMPA receptor GluA2 subunit in astrocytes via activation of protein kinase C signaling pathway

期刊名称：

GLIA

PMID：

30883902

影响因子：

5.829

应用范围：

WB,IP

检测物种：

Rat

发表时间：

2019-03-18

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CY6628

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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