NEDD8 Ab
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NEDD8 Ab
Western blot analysis of NEDD8 expression in K562 cell lysate.
NEDD8 Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
NEDD8 Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
NEDD8 Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
NEDD8 Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
NEDD8 Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
NEDD8 Ab
NEDD8 Ab
NEDD8 Ab
NEDD8 Ab
NEDD8 Ab
NEDD8 Ab

产品简介

Product Introduction

Catalog No.

CY6622

Source

Recombinant Rabbit mAb

UniProt ID

Q15843

Reactivity

Human;Mouse;Rat

Application

WB;IHC;ICC/IF;IHF;IP

Calculated Mol Weight

9 kDa

Observed Mol Weight

10, 90 kDa

Recommended Dilution

WB 1:1000-1:2000

IHC 1:100-1:200

ICC/IF 1:50-1:200

IHF 1:50-1:200

IP 1:20-1:50

Alternative Names

NEDD8; Nedd-8;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human NEDD8

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis via its conjugation to a limited number of cellular proteins, such as cullins or p53/TP53.Attachment of NEDD8 to cullins is critical for the recruitment of E2 to the cullin-RING-based E3 ubiquitin-protein ligase complex, thus facilitating polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins.

引用文献

Citation

MLN4924 alleviates autoimmune myocarditis by promoting Act1 degradation and blocking Act1-mediated mRNA stability

期刊名称：

INTERNATIONAL IMMUNOPHARMACOLOGY

PMID：

39038386

影响因子：

4.8

应用范围：

WB

检测物种：

Mouse,Rat

发表时间：

2024-07-21

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CY6622

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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