p-IRF3 (S386) Ab
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p-IRF3 (S386) Ab
Western blot analysis of Phospho-IRF3 (S386) expression in MCF7 cell lysate.
p-IRF3 (S386) Ab
SOD2 Facilitates the Antiviral Innate Immune Response by Scavenging Reactive Oxygen Species. -Viral Immunology
p-IRF3 (S386) Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
p-IRF3 (S386) Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
p-IRF3 (S386) Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
p-IRF3 (S386) Ab
p-IRF3 (S386) Ab
p-IRF3 (S386) Ab

产品简介

Product Introduction

Catalog No.

CY6575

Source

Recombinant Rabbit mAb

UniProt ID

Q14653

Reactivity

Human

Application

WB;ICC/IF

Calculated Mol Weight

47 kDa

Observed Mol Weight

55 kDa

Recommended Dilution

WB 1:1000-1:2000

ICC/IF 1:50-1:200

Alternative Names

IRF3; Interferon regulatory factor 3;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Phosphorylated

Immunogen

A synthesized peptide derived from human IRF3 around the phosphorylation site of S386

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. The protein plays an important role in the innate immune response against DNA and RNA viruses.

引用文献

Citation

SOD2 Facilitates the Antiviral Innate Immune Response by Scavenging Reactive Oxygen Species

期刊名称：

VIRAL IMMUNOLOGY

PMID：

28574756

影响因子：

1.432

应用范围：

WB

检测物种：

Human,Mouse

发表时间：

2017-10-01
SARS-CoV-2 NSP5 and N protein counteract the RIG-I signaling pathway by suppressing the formation of stress granules

期刊名称：

Signal Transduction and Targeted Therapy

PMID：

35075101

影响因子：

38.104

应用范围：

WB

检测物种：

Human

发表时间：

2022-01-24
DLG1 promotes the antiviral innate immune response by inhibiting p62-mediated autophagic degradation of IKKε

期刊名称：

JOURNAL OF VIROLOGY

PMID：

37982618

影响因子：

5.4

应用范围：

WB

检测物种：

Mouse

发表时间：

2023-11-20
Arginine methylation-dependent cGAS stability promotes non-small cell lung cancer cell proliferation

期刊名称：

CANCER LETTERS

PMID：

38331088

影响因子：

9.1

应用范围：

WB

检测物种：

Human

发表时间：

2024-02-07

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CY6575

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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