LC3B Ab - Abways

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LC3B Ab

Instructions

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All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.

All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.

Western blot analysis of LC3B expression in (1) Human brain lysate; (2) RAW 264.7 cell lysate; (3) C6 cell lysate.

SIRT 5‐mediated deacetylation of LDHB promotes autophagy and tumorigenesis in colorectal cancer. -Molecular Oncology

Prostaglandin E1 Inhibited Diabetes-Induced Phenotypic Switching of Vascular Smooth Muscle Cells Through Activating Autophagy. -Cellular Physiology and Biochemistry

Introduction

Citation

User feedback

产品简介

Product Introduction

Catalog No.

CY5992

Source

Recombinant Rabbit mAb

UniProt ID

Q9GZQ8

Reactivity

Human;Mouse;Rat

Application

WB;IHC;ICC/IF;IHF;IP

Calculated Mol Weight

15 kDa

Observed Mol Weight

14, 16 kDa

Recommended Dilution

WB 1:1000-1:2000

IHC 1:100-1:200

ICC/IF 1:50-1:200

IHF 1:50-1:200

IP 1:20-1:50

Alternative Names

ATG8F; LC3B; MAP1LC3B; MLP3B; MAP1LC3B;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human LC3B

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Ubiquitin-like modifier involved in formation of autophagosomal vacuoles.Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.In response to cellular stress and upon mitochondria fission, binds C-18 ceramides and anchors autophagolysosomes to outer mitochondrial membranes to eliminate damaged mitochondria.

引用文献

Citation

Exosomes derived from human umbilical cord mesenchymal stem cells pretreated by monosialoteterahexosyl ganglioside alleviate intracerebral hemorrhage by down-regulating autophagy

期刊名称：

EXPERIMENTAL CELL RESEARCH

PMID：

38311048

影响因子：

3.3

应用范围：

检测物种：

Human,Rat

发表时间：

2024-02-03

Inhibition of TNBC Cell Growth by Paroxetine: Induction of Apoptosis and Blockage of Autophagy Flux

期刊名称：

Cancers

PMID：

38473249

影响因子：

4.5

应用范围：

检测物种：

Human,Mouse

发表时间：

2024-02-22

Resveratrol activates autophagy and protects from UVA-induced photoaging in human skin fibroblasts and the skin of male mice by regulating the AMPK pathway

期刊名称：

BIOGERONTOLOGY

PMID：

38592565

影响因子：

4.4

应用范围：

WB,ICC/IF

检测物种：

Human,Mouse

发表时间：

2024-04-09

ACADM inhibits AMPK activation to modulate PEDV-induced lipophagy and β-oxidation for impairing viral replication

期刊名称：

JOURNAL OF BIOLOGICAL CHEMISTRY

PMID：

39002673

影响因子：

应用范围：

检测物种：

Monkey

发表时间：

2024-07-11

Stimulation by exosomes from hypoxia-preconditioned hair follicle mesenchymal stem cells facilitates mitophagy by inhibiting the PI3K/AKT/mTOR signaling pathway to alleviate ulcerative colitis

期刊名称：

Theranostics

PMID：

39113800

影响因子：

12.4

应用范围：

WB,ICC/IF

检测物种：

Mouse

发表时间：

2024-07-08

Melanin resistance of heat-processed ginsenosides from Panax ginseng berry treated with citric acid through autophagy pathway

期刊名称：

BIOORGANIC CHEMISTRY

PMID：

39216197

影响因子：

4.5

应用范围：

WB,ICC/IF

检测物种：

Mouse

发表时间：

2024-08-25

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CY5992

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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