LC3B Ab
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LC3B Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
LC3B Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
LC3B Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
LC3B Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
LC3B Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
LC3B Ab
Western blot analysis of LC3B expression in (1) Human brain lysate; (2) RAW 264.7 cell lysate; (3) C6 cell lysate.
LC3B Ab
SIRT 5‐mediated deacetylation of LDHB promotes autophagy and tumorigenesis in colorectal cancer. -Molecular Oncology
LC3B Ab
Prostaglandin E1 Inhibited Diabetes-Induced Phenotypic Switching of Vascular Smooth Muscle Cells Through Activating Autophagy. -Cellular Physiology and Biochemistry

产品简介

Product Introduction

Catalog No.

CY5992

Source

Recombinant Rabbit mAb

UniProt ID

Q9GZQ8

Reactivity

Human;Mouse;Rat

Application

WB;IHC;ICC/IF;IHF;IP

Calculated Mol Weight

15 kDa

Observed Mol Weight

14, 16 kDa

Recommended Dilution

WB 1:1000-1:2000

IHC 1:100-1:200

ICC/IF 1:50-1:200

IHF 1:50-1:200

IP 1:20-1:50

Alternative Names

ATG8F; LC3B; MAP1LC3B; MLP3B; MAP1LC3B;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human LC3B

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Ubiquitin-like modifier involved in formation of autophagosomal vacuoles.Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.In response to cellular stress and upon mitochondria fission, binds C-18 ceramides and anchors autophagolysosomes to outer mitochondrial membranes to eliminate damaged mitochondria.

引用文献

Citation

Exogenous supplement of glucagon like peptide-1 protects the heart against aortic banding induced myocardial fibrosis and dysfunction through inhibiting mTOR/p70S6K signaling and promoting autophagy

期刊名称：

EUROPEAN JOURNAL OF PHARMACOLOGY

PMID：

32621911

影响因子：

3.263

应用范围：

WB

检测物种：

Rat

发表时间：

2020-07-01
Swainsonine promotes apoptosis by impairing lysosomal function and inhibiting autophagic degradation in rat primary renal tubular epithelial cells

期刊名称：

CHEMICO-BIOLOGICAL INTERACTIONS

PMID：

33186601

影响因子：

3.723

应用范围：

WB

检测物种：

Rat

发表时间：

2020-11-10
Chaetoglobosin G inhibits proliferation, autophagy and cell cycle of lung cancer cells through EGFR/MEK/ERK signaling pathway

期刊名称：

PHARMAZIE

PMID：

33303057

影响因子：

1.198

应用范围：

WB

检测物种：

Human

发表时间：

2020-12-01
Fucoxanthin rescues dexamethasone induced C2C12 myotubes atrophy

期刊名称：

BIOMEDICINE & PHARMACOTHERAPY

PMID：

33865017

影响因子：

6.53

应用范围：

WB

检测物种：

Mouse

发表时间：

2021-04-14
The antiandrogenic effect of neferine, liensinine, and isoliensinine by inhibiting 5-α-reductase and androgen receptor expression via PI3K/AKT signaling pathway in prostate cancer

期刊名称：

PHARMAZIE

PMID：

33964997

影响因子：

1.267

应用范围：

WB

检测物种：

Human

发表时间：

2021-05-01
SARS-CoV-2 ORF10 suppresses the antiviral innate immune response by degrading MAVS through mitophagy

期刊名称：

Cellular & Molecular Immunology

PMID：

34845370

影响因子：

11.53

应用范围：

WB

检测物种：

Human

发表时间：

2021-11-29

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CY5992

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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