Integrin alpha 5 Ab
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Integrin alpha 5 Ab
Western blot analysis of Integrin alpha 5 expression in Mouse heart lysate.
Integrin alpha 5 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
Integrin alpha 5 Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
Integrin alpha 5 Ab
Immunofluorescent analysis of MCF-7 cells, using Integrin alpha 5 Antibody.
Integrin alpha 5 Ab
Integrin alpha 5 Ab
Integrin alpha 5 Ab
Integrin alpha 5 Ab
Integrin alpha 5 Ab
Integrin alpha 5 Ab
Integrin alpha 5 Ab
Integrin alpha 5 Ab

产品简介

Product Introduction

Catalog No.

CY5979

Source

Recombinant Rabbit mAb

UniProt ID

P08648

Reactivity

Human;Mouse;Rat

Application

WB;IHC;ICC/IF;IHF;IP;FC

Calculated Mol Weight

115 kDa

Observed Mol Weight

150 kDa

Recommended Dilution

WB 1:1000-1:2000

IHC 1:100-1:200

ICC/IF 1:50-1:200

IHF 1:50-1:200

IP 1:20-1:50

FC 1:20-1:100

Alternative Names

Integrin alpha-5; VLA-5; CD49e; ITGA5; FNRA;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human Integrin alpha 5

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Integrin alpha-5/beta-1 (ITGA5:ITGB1) is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. ITGA5:ITGB1 binds to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1.

引用文献

Citation

Integrin α5β1, as a Receptor of Fibronectin, Binds the FbaA Protein of Group A Streptococcus To Initiate Autophagy during Infection

期刊名称：

mBio

PMID：

32518187

影响因子：

6.784

应用范围：

WB

检测物种：

Human,Mouse

发表时间：

2020-06-30
Persistence Infection of TGEV Promotes Enterococcus faecalis Infection on IPEC-J2 Cells

期刊名称：

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

PMID：

36613893

影响因子：

6.208

应用范围：

WB,ICC/IF

检测物种：

Pig

发表时间：

2022-12-27
Based on Weighted Gene Co-Expression Network Analysis Reveals the Hub Immune Infiltration-Related Genes Associated with Ulcerative Colitis

期刊名称：

Journal of Inflammation Research

PMID：

38250142

影响因子：

4.2

应用范围：

IHC

检测物种：

Human

发表时间：

2024-01-16
Eliminating the invading extracellular and intracellular FnBp+ bacteria from respiratory epithelial cells by autophagy mediated through FnBp-Fn-Integrin α5β1 axis

期刊名称：

Frontiers in Cellular and Infection Microbiology

PMID：

38264727

影响因子：

4.6

应用范围：

WB,Pull Down

检测物种：

Mouse,Human

发表时间：

2024-01-09
Innovative nebulization delivery of lipid nanoparticle-encapsulated siRNA: a therapeutic advance for Staphylococcus aureus-induced pneumonia

期刊名称：

Journal of Translational Medicine

PMID：

39407291

影响因子：

6.1

应用范围：

WB

检测物种：

Mouse

发表时间：

2024-10-15

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CY5979

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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>> All rabbit monoclonal antibody products targeting this target