FOXO4 Ab
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FOXO4 Ab
Western blot analysis of FoxO4 expression in human heart lysate.
FOXO4 Ab
Immunofluorescent analysis of Hela cells, using FoxO4 Antibody.
FOXO4 Ab
FOXO4 Ab
FOXO4 Ab
FOXO4 Ab
FOXO4 Ab
FOXO4 Ab

产品简介

Product Introduction

Catalog No.

CY5892

Source

Recombinant Rabbit mAb

UniProt ID

P98177

Reactivity

Human;Mouse;Rat

Application

WB;ICC/IF;IP;FC

Calculated Mol Weight

54 kDa

Observed Mol Weight

65 kDa

Recommended Dilution

WB 1:1000-1:2000

ICC/IF 1:50-1:200

IP 1:20-1:50

FC 1:20-1:100

Alternative Names

Forkhead box protein O4; Fork head domain transcription factor AFX1; AFX; AFX1; MLLT7; FOXO4;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human FOXO4

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Transcription factor involved in the regulation of the insulin signaling pathway. Binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. Down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. Also involved in negative regulation of the cell cycle. Involved in increased proteasome activity in embryonic stem cells (ESCs) by activating expression of PSMD11 in ESCs, leading to enhanced assembly of the 26S proteasome, followed by higher proteasome activity.

引用文献

Citation

Hydroxysafflor yellow A ameliorates alcohol-induced liver injury through PI3K/Akt and STAT3/NF-κB signaling pathways

期刊名称：

PHYTOMEDICINE

PMID：

38878526

影响因子：

6.7

应用范围：

WB

检测物种：

Mouse,Human

发表时间：

2024-06-08

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CY5892

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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