MEK5 Ab
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MEK5 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
MEK5 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
MEK5 Ab
Western blot analysis of MEK5 expression in Hela cell lysate.
MEK5 Ab
MEK5 Ab
MEK5 Ab
MEK5 Ab
MEK5 Ab

产品简介

Product Introduction

Catalog No.

CY5869

Source

Recombinant Rabbit mAb

UniProt ID

Q13163

Reactivity

Human

Application

WB;ICC/IF

Calculated Mol Weight

50 kDa

Observed Mol Weight

49 kDa

Recommended Dilution

WB 1:1000-1:2000

ICC/IF 1:50-1:200

Alternative Names

MAP2K5; HsT17454; MAPKK 5; MEK 5; MAPKK5; MEK5; MKK5; MAP kinase kinase 5; PRKMK5; MAP kinase kinase MEK5b; MAPK/ERK kinase 5;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human MEK5

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Acts as a scaffold for the formation of a ternary MAP3K2/MAP3K3-MAP3K5-MAPK7 signaling complex. Activation of this pathway appears to play a critical role in protecting cells from stress-induced apoptosis, neuronal survival and cardiac development and angiogenesis. As part of the MAPK/ERK signaling pathway, acts as a negative regulator of apoptosis in cardiomyocytes via promotion of STUB1/CHIP-mediated ubiquitination and degradation of ICER-type isoforms of CREM.

引用文献

Citation

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CY5869

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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