p-SMAD2 (S255) Ab
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p-SMAD2 (S255) Ab
Western blot analysis of Phospho-Smad2 (S255) expression in Hela cell treated with Okadaic acid and Calyculin A lysate.
p-SMAD2 (S255) Ab
Immunohistochemical analysis of paraffin-embedded human transitional cell carcinoma of bladder, using Phospho-Smad2 (S255) Antibody.
p-SMAD2 (S255) Ab
p-SMAD2 (S255) Ab
p-SMAD2 (S255) Ab
p-SMAD2 (S255) Ab
p-SMAD2 (S255) Ab
p-SMAD2 (S255) Ab

产品简介

Product Introduction

Catalog No.

CY5859

Source

Recombinant Rabbit mAb

UniProt ID

Q15796

Reactivity

Human;Mouse;Rat

Application

WB;IHC;IP

Calculated Mol Weight

52 kDa

Observed Mol Weight

52 kDa

Recommended Dilution

WB 1:1000-1:2000

IHC 1:100-1:200

IP 1:20-1:50

Alternative Names

JV18-1, MADH2, MADR2, Mad-related protein 2, Mothers against DPP homolog 2, Mothers against decapentaplegic homolog 2, Smad 2;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Phosphorylated

Immunogen

A synthesized peptide derived from human SMAD2 around the phosphorylation site of S255

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. Promotes TGFB1-mediated transcription of odontoblastic differentiation genes in dental papilla cells (By similarity).

引用文献

Citation

Luteolin inhibits the TGF-β signaling pathway to overcome bortezomib resistance in multiple myeloma

期刊名称：

CANCER LETTERS

PMID：

36442773

影响因子：

9.756

应用范围：

WB

检测物种：

Human,Mouse

发表时间：

2022-11-26

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CY5859

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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