p-SMAD2 (S250) Ab
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p-SMAD2 (S250) Ab
Western blot analysis of Phospho-Smad2 (S250) expression in (1) HeLa cell treated with alkaline phosphatase lysate; (2) HeLa cell lysate.
p-SMAD2 (S250) Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
p-SMAD2 (S250) Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
p-SMAD2 (S250) Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
p-SMAD2 (S250) Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
p-SMAD2 (S250) Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
p-SMAD2 (S250) Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
p-SMAD2 (S250) Ab

产品简介

Product Introduction

Catalog No.

CY5857

Source

Recombinant Rabbit mAb

UniProt ID

Q15796

Reactivity

Human;Mouse;Rat

Application

WB;FC

Calculated Mol Weight

52 kDa

Observed Mol Weight

58 kDa

Recommended Dilution

WB 1:1000-1:2000

FC 1:20-1:100

Alternative Names

JV18-1, MADH2, MADR2, Mad-related protein 2, Mothers against DPP homolog 2, Mothers against decapentaplegic homolog 2, Smad 2;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Phosphorylated

Immunogen

A synthesized peptide derived from human SMAD2 around the phosphorylation site of S250

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. Promotes TGFB1-mediated transcription of odontoblastic differentiation genes in dental papilla cells (By similarity).

引用文献

Citation

MiR-20a-3p regulates TGF-β1/Survivin pathway to affect keratinocytes proliferation and apoptosis by targeting SFMBT1 in vitro

期刊名称：

CELLULAR SIGNALLING

PMID：

29886071

影响因子：

3.487

应用范围：

WB

检测物种：

Human

发表时间：

2018-06-07
miR-744-5p suppresses tumor proliferation and metastasis by targeting transforming growth factor-beta 1 (TGF-β1) in hepatocellular carcinoma (HCC)

期刊名称：

Journal of Gastrointestinal Oncology

PMID：

34532130

影响因子：

2.892

应用范围：

WB

检测物种：

Human

发表时间：

2021-08-01

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CY5857

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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