p-PLK1 (T20) Ab
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p-PLK1 (T20) Ab
Western blot analysis of Phospho-PLK1 (T210) expression in (1) HeLa cell lysate; (2) HeLa cell treated with nocodazole lysate.
p-PLK1 (T20) Ab
p-PLK1 (T20) Ab
p-PLK1 (T20) Ab
p-PLK1 (T20) Ab
p-PLK1 (T20) Ab
p-PLK1 (T20) Ab
p-PLK1 (T20) Ab

产品简介

Product Introduction

Catalog No.

CY5844

Source

Recombinant Rabbit mAb

UniProt ID

P53350

Reactivity

Human

Application

WB

Calculated Mol Weight

68 kDa

Observed Mol Weight

68 kDa

Recommended Dilution

WB 1:1000-1:2000

Alternative Names

Cell cycle regulated protein kinase; PLK 1; PLK; Polo like kinase 1 ; Serine/threonine protein kinase 13; Serine/threonine protein kinase PLK1; STPK 13;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Phosphorylated

Immunogen

A synthesized peptide derived from human PLK1 around the phosphorylation site of T20

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Serine/threonine-protein kinase that performs several important functions throughout M phase of the cell cycle, including the regulation of centrosome maturation and spindle assembly, the removal of cohesins from chromosome arms, the inactivation of anaphase-promoting complex/cyclosome (APC/C) inhibitors, and the regulation of mitotic exit and cytokinesis.

引用文献

Citation

Novel Dual BET and PLK1 Inhibitor WNY0824 Exerts Potent Antitumor Effects in CRPC by Inhibiting Transcription Factor Function and Inducing Mitotic Abnormality

期刊名称：

MOLECULAR CANCER THERAPEUTICS

PMID：

32220972

影响因子：

5.615

应用范围：

WB

检测物种：

Human

发表时间：

2020-06-02

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CY5844

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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