IRS 1 Ab
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IRS 1 Ab
Western blot analysis of IRS1 expression in HEK293 cell lysate.
IRS 1 Ab
Immunofluorescent analysis using the Antibody at 1:50 dilution.
IRS 1 Ab
Immunofluorescent analysis using the Antibody at 1:50 dilution.
IRS 1 Ab
Immunofluorescent analysis using the Antibody at 1:100 dilution.
IRS 1 Ab
IRS 1 Ab
IRS 1 Ab
IRS 1 Ab

产品简介

Product Introduction

Catalog No.

CY5830

Source

Recombinant Rabbit mAb

UniProt ID

P35568

Reactivity

Human

Application

WB;IHC;ICC/IF;IHF

Calculated Mol Weight

132 kDa

Observed Mol Weight

170 kDa

Recommended Dilution

WB 1:1000-1:2000

IHC 1:100-1:200

ICC/IF 1:50-1:200

IHF 1:50-1:200

Alternative Names

HIRS1; Insulin receptor substrate 1; IRS 1; IRS1;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human IRS 1

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

IRS-1 is an adaptor protein that is one of the major substrates of the insulin receptor kinase. Contains multiple tyrosine phosphorylation motifs that serve as docking sites for SH2-domain-containing proteins including phosphatidylinositol 3-kinase p85 subunit and GRB-2.

引用文献

Citation

Acid Sphingomyelinase Down-regulation Alleviates Vascular Endothelial Insulin Resistance in Diabetic Rats

期刊名称：

BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

PMID：

29923306

影响因子：

2.659

应用范围：

WB,IHC,ICC/IF

检测物种：

Rat

发表时间：

2018-06-19
The identities of insulin signaling pathway are affected by overexpression of Tau and its phosphorylation form

期刊名称：

Frontiers in Aging Neuroscience

PMID：

36589543

影响因子：

5.702

应用范围：

WB,ICC/IF,IP

检测物种：

Human

发表时间：

2022-12-16

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CY5830

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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